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Volume 15, Number 6—June 2009

Dispatch

Merkel Cell Polyomavirus Strains in Patients with Merkel Cell Carcinoma

Antoine Touzé, Julien Gaitan, Annabel Maruani, Emmanuelle Le Bidre, Angélique Doussinaud, Christine Clavel, Anne Durlach, François Aubin, Serge Guyétant, Gérard Lorette, and Pierre CoursagetComments to Author 
Author affiliations: Institut National de la Santé et de la Recherche Médicale (INSERM) Unit 618, Tours, France (A. Touzé, J. Gaitan, A. Doussinaud, P. Coursaget); Université François Rabelais, Tours (A. Touzé, J. Gaitan, A. Doussinaud, S. Guyétant, G. Lorette, P. Coursaget, A. Maruani, E. Le Bidre); Centre Hospitalier Régional Universitaire (CHRU)–Trousseau, Tours (A. Maruani, E. Le Bidre, S. Guyétant, G. Lorette); INSERM Unit 903, Reims, France (C. Clavel, A. Durlach); CHRU de Reims (C. Clavel, A. Durlach); Université de Franche–Comté, Hôpital Saint-Jacques, Besançon, France (F. Aubin)

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Table

Detection of Merkel cell polyomavirus by PCR in patients with Merkel cell carcinoma using primers sets within LT and VP gene sequences, France, 2008*

Sample No. patients LT1, no. (%) VP1, no. (%) Total, no. (%)
Merkel cell carcinoma
Paraffin-embedded 20 6 (30) 6 (30) 9 (45)
Frozen tissue
12
10 (83)
12 (100)
12 (100)
Other neuroendocrine carcinomas
Paraffin-embedded 1 0 0 0
Frozen tissue 8 0 0 0

*Non–Merkel cell carcinoma high-grade neuroendocrine carcinomas were 5 small-cell lung carcinomas, 3 well-differentiated intestinal carcinomas, and 1 high-grade neuroendocrine carcinoma of the cervix.

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