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Volume 15, Number 6—June 2009

CME ACTIVITY

Past, Present, and Possible Future Human Infection with Influenza Virus A Subtype H7

Jessica A. Belser, Carolyn B. Bridges, Jacqueline M. Katz, and Terrence M. TumpeyComments to Author 
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (J.A. Belser, C.B. Bridges, J.M. Katz, T.M. Tumpey); Mount Sinai School of Medicine, New York, New York, USA (J.A. Belser)

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Table

Cases of human subtype H7 influenza A virus infection since 1996*

Location Year Subtype IVPI No. human infections Symptoms References
UK (England) 1996 H7N7 LPAI 1 Conjunctivitis (8,9)
USA (Virginia) 2002 H7N2 LPAI 1† Respiratory (10)
USA (New York) 2003 H7N2 LPAI 1 Respiratory (11)
Italy 2002–03 H7N3 LPAI 7† Conjunctivitis, respiratory (12)
The Netherlands 2003 H7N7 HPAI 89 Conjunctivitis, respiratory (6,13)
Canada (British Columbia) 2004 H7N3 LPAI/HPAI 2 Conjunctivitis, respiratory (14,15)
UK (Norfolk) 2006 H7N3 LPAI 1 Conjunctivitis (16)
UK (Wales) 2007 H7N2 LPAI 4 Conjunctivitis, respiratory (17)

*IVPI, intravenous pathogenicity index (1); LPAI, low pathogenicity avian influenza; HPAI, highly pathogenic avian influenza.
†Serologic evidence only.

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