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Volume 15, Number 7—July 2009

Research

Clusters of Multidrug-Resistant Mycobacterium tuberculosis Cases, Europe

Isabelle DevauxComments to Author , Kristin Kremer, Herre Heersma, and Dick van Soolingen
Author affiliations: European Centre for Disease Prevention and Control, Stockholm, Sweden (I. Devaux); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (K. Kremer, H. Heersma, D. Van Soolingen)

Main Article

Table 5

Predictors for TB caused by Beijing strains among 506 cases reported in 16 European countries, January 2003 through June 2007*

Variable MDR TB strains
Unadjusted OR (95% CI) Adjusted† OR (95% CI)
No. patients % Beïjing strains
Sex
Male 333 58 1 1
Female
164
55
0.9 (0.6–1.3)
1.1 (0.5–2.4)
Age
15–44 313 53 1 1
45–64 142 67 1.7 (1.1–2.6) 1.0 (0.5–2.1)
>65
30
70
2.5 (1.1–5.5)
2.3 (0.5–10.4)
Origin
Baltic states 188 92 154.5 (54.0–442.0) 173.8 (45.5–663.6)
Other FSU countries‡ 99 75 39.7 (14.4–109.5) 32.2 (8.6–120.8)
Other European countries 71 6 1 1
Africa
71
10
1.5 (0.4–4.9)
1.1 (0.2–5.5)
Site of disease
Pulmonary 455 59 3.4 (1.7–6.6) 0.7 (0.1–3.3)
Extrapulmonary
40
30
1
1
Previous TB
Yes 156 64 1.1 (0.8–1.7) 1.0 (0.5–2.0)
No
245
62
1
1
Clustering
Yes 250 87% 19.0 (12.0–30.3)
No
250
26%
1

XDR TB
Yes 51 90 5.5 (2.1–14.3)
No 341 62 1

*TB, tuberculosis; MDR, multidrug-resistant; OR, odds ratio; CI, confidence interval; FSU, former Soviet Union; XDR, extensively drug-resistant. Boldface indicates significance.
†For all other factors in the model except XDR TB.
‡Former Soviet Union countries: Azerbaijan, Belarus, Georgia, Kazakhstan, Kyrgyzstan, Moldova, Russia, Tajikistan, Ukraine, and Uzbekistan.

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