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Volume 16, Number 10—October 2010

Dispatch

Predicting Need for Hospitalization of Patients with Pandemic (H1N1) 2009, Chicago, Illinois, USA

Shawn Vasoo, Kamaljit SinghComments to Author , and Gordon M. Trenholme
Author affiliations: Author affiliation: Rush University Medical Center, Chicago, Illinois, USA

Main Article

Table 1

Demographics of nonhospitalized and hospitalized patients who had pandemic (H1N1) 2009 infection, Rush University Medical Center, Chicago, Illinois, USA, April 29–June 22, 2009*

Characteristic Nonhospitalized patients, n = 51 Hospitalized patients, 
n = 32 ICU patients,
n = 16 Nonhospitalized vs. hospitalized patients
ICU vs. non–ICU patients†
p value OR 
(95% CI) p value OR 
(95% CI)
Median age, y (IQR) 20.0 
(9.0–28.0) 12.0 
(2.0–38.8) 2.5 
(1.13–31.8) 0.70‡ 0.16‡
Age <5 y, no. (%) 8 (15.7) 12 (37.5) 9 (56.3) 0.02§ 3.2 
(1.1–9.1) 0.002 6.6 
(2.0–21.3)
Sex, M/F (% M) 23/28 (45.1) 12/20 (37.5) 5/11 (31.3) 0.50§ 0.73 
(0.30–1.8) 0.33§ 0.56 
(0.18–1.8)
Presence of high- risk conditions,¶ no. (%) 21 (41.2) 29 (90.6) 16 (100) <0.0001§ 13.8 
(3.7–51.3) <0.0001
No. high-conditions per patient,¶ median (range) 0 (0–2) 2 (0–4) 2 (1–3) <0.0001‡# <0.0001‡
Chronic pulmonary disease, no. (%) 11 (21.6) 13 (40.6) 9 (56.3) 0.06§ 2.5
(0.94–6.6) 0.01 4.5 
(1.4–14.0)
History of prematurity, no. (%) 0 6 (18.8) 5 (31.3) 0.002 0.001 30.0 
(3.2–281.8)
Congenital heart disease,** no. (%) 0 2 (6.3) 2 (12.5) 0.15 0.04
Transplantation,†† no. (%) 1 (2.0) 3 (9.4) 1 (6.3) 0.29 5.2 
(0.51–52.1) 1.00 1.4 
(0.14–14.6)
Hemoglobinopathy, no. (%) 0 4 (12.5) 2 (12.5) 0.02 0.17 4.6 
(0.6–35.8)
Diabetes mellitus, no. (%) 3 (5.9) 5 (15.6) 3 (18.8) 0.25 3.0 
(0.66–13.4) 0.18 2.9 
(0.6–13.5)
Chronic neurologic disease 2 (3.9) 7 (21.9) 4 (25.0) 0.02 6.9 
(1.3–35.5) 0.07 4.1 
(1.0–17.7)
Immunosuppression, no. (%) 2 (3.9) 5 (15.6) 3 (18.8) 0.10 4.5 
(0.82–25.0) 0.13 3.6 
(0.7–18.2)
Malignancy, no. (%) 0 3 (9.4) 1 (6.3) 0.054 0.48 2.2 
(0.2–25.5)
Pregnancy, no. (%)‡‡ 1 (4) 3 (15.0) 0 0.29 4.8 
(0.46–49.6) 0.56

*p values by Fisher exact test except as indicated. ICU, intensive care unit; OR, odds ratio; CI, confidence interval; IQR, interquartile range; –, not applicable.
†Nonhospitalized patients + hospitalized patients not in ICU; n = 67.
‡Mann-Whitney U test.
§Pearson 2-sided χ2 test.
¶High-risk conditions as defined by Centers for Disease Control and Prevention: <5 y or >65 y; pregnancy; immunosuppression; chronic pulmonary, cardiovascular, hepatic, hematologic, neurologic, neuromuscular, or metabolic disorders; long-term aspirin therapy in those <18 y of age.
#Significant on multivariate analysis.
**Tetralogy of Fallot (1), patent ductus arteriosus status postmedical closure (1).
†† Renal transplant (2), liver transplant (1), heart transplant (1).
‡‡Percentage of female patients.

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