Emerging Infectious Disease ISSN: 1080-6059

Enterovirus 75 Encephalitis in Children, Southern India

Penny Lewthwaite

, David Perera, Mong How Ooi, Anna Last, Ravi Kumar, Anita Desai, Ashia Begum, Vasanthapuram Ravi, M. Veera Shankar, Phaik Hooi Tio, Mary Jane Cardosa, and Tom Solomon

Author affiliations: University of Liverpool, Liverpool, UK (P. Lewthwaite, M.H. Ooi, A. Last, T. Solomon); Universiti Malaysia Sarawak, Sarawak, Malaysia (D. Perera, M.H. Ooi, P.H. Tio, M.J. Cardosa); Sibu Hospital, Sibu, Sarawak (M.H. Ooi); Vijayanagar Institute of Medical Sciences, Karnataka, India (R. Kumar, A. Begum, M. Veera Shankar); National Institute of Mental Health and Neurological Sciences, Bangalore, India (R. Kumar, A. Desai, V. Ravi)

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Figure

Phylogenetic analysis of viral protein 1 enterovirus 75 (EV75) nucleotide sequences. The tree was constructed by using the neighbor-joining method and the maximum-composite likelihood-substitution model. Significance of phylogenies was investigated by bootstrap analysis with 1,000 pseudoreplicate datasets. Bootstrap values >70% are indicated on the tree. Closed circles indicate isolates from India (this study) and open circles previously reported EV75 sequences. All EV75 sequences are named b

Figure. Phylogenetic analysis of viral protein 1 enterovirus 75 (EV75) nucleotide sequences. The tree was constructed by using the neighbor-joining method and the maximum-composite likelihood-substitution model. Significance of phylogenies was investigated by bootstrap analysis with 1,000 pseudoreplicate datasets. Bootstrap values >70% are indicated on the tree. Closed circles indicate isolates from India (this study) and open circles previously reported EV75 sequences. All EV75 sequences are named by using the conventional GenBank accession numbers (published sequences) or sample name (sequences from this study), country of origin, and year of isolation (where available). All prototype EV reference sequences are indicated by their GenBank accession numbers preceding serotype identification. Scale bar indicates nucleotide substitutions per site.

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