Emerging Infectious Disease ISSN: 1080-6059

Serologic Markers for Detecting Malaria in Areas of Low Endemicity, Somalia, 2008

Teun Bousema

, Randa M. Youssef, Jackie Cook, Jonathan Cox, Victor A. Alegana, Jamal Amran, Abdisalan M. Noor, Robert W. Snow, and Chris Drakeley

Author affiliations: London School of Hygiene and Tropical Medicine, London, UK (T. Bousema, J. Cook, J. Cox, C. Drakeley); University of Alexandria, Alexandria, Egypt (R.M. Youssef); Kenya Medical Research Institute–Wellcome Trust Research Programme, Nairobi, Kenya (R.M. Youssef, V.A. Alegana, J. Amran, A.M. Noor, R.W. Snow); Roll Back Malaria–World Health Organization, Hargeisa, Somalia (J. Amran); University of Oxford, Oxford, UK (A.M. Noor, R.W. Snow)

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Figure 1

Seroprevalence data for antibodies against A) Plasmodium falciparum merozoite surface protein 119 (MSP-119), B) P. falciparum apical membrane antigen 1 (AMA-1), C) P. vivax MSP-119, and D) P. vivax AMA-1 by age in the study population, Somalia, 2008. Gray lines indicate 95% confidence intervals. Seroconversion rates (95% confidence intervals) were as follows: P. falciparum MSP-119 0.0082 (0.0068–0.097); AMA-1 0.0053 (0.0042–0.0066); P. vivax MSP-119 0.0086 (0.0055–0.0133); AMA-1 0.0075 (0.0050–0

Figure 1. Seroprevalence data for antibodies against A) Plasmodium falciparum merozoite surface protein 1₁₉ (MSP-1₁₉), B) P. falciparum apical membrane antigen 1 (AMA-1), C) P. vivax MSP-1₁₉, and D) P. vivax AMA-1 by age in the study population, Somalia, 2008. Gray lines indicate 95% confidence intervals. Seroconversion rates (95% confidence intervals) were as follows: P. falciparum MSP-1₁₉ 0.0082 (0.0068–0.097); AMA-1 0.0053 (0.0042–0.0066); P. vivax MSP-1₁₉ 0.0086 (0.0055–0.0133); AMA-1 0.0075 (0.0050–0.0112).

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