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Volume 16, Number 3—March 2010

Research

Serologic Markers for Detecting Malaria in Areas of Low Endemicity, Somalia, 2008

Teun BousemaComments to Author , Randa M. Youssef, Jackie Cook, Jonathan Cox, Victor A. Alegana, Jamal Amran, Abdisalan M. Noor, Robert W. Snow, and Chris Drakeley
Author affiliations: London School of Hygiene and Tropical Medicine, London, UK (T. Bousema, J. Cook, J. Cox, C. Drakeley); University of Alexandria, Alexandria, Egypt (R.M. Youssef); Kenya Medical Research Institute–Wellcome Trust Research Programme, Nairobi, Kenya (R.M. Youssef, V.A. Alegana, J. Amran, A.M. Noor, R.W. Snow); Roll Back Malaria–World Health Organization, Hargeisa, Somalia (J. Amran); University of Oxford, Oxford, UK (A.M. Noor, R.W. Snow)

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Table 2

Immune responses against Plasmodium falciparum and P. vivax in study participants, by village, Somalia, 2008*

333.9 (271.4–463.9) 342.4 (280.1–374.8) 291.5 (248.7–393.3) 0.39
AMA-1 5.2 (13/252) 7.4 (11/149) 12.8 (85/665) 0.001
151.5 (146.0–202.1) 183.5 (155.7–275.7) 227.1 (184.6–390.8) 0.10

*IQR, interquartile range (25th–75th percentile); MSP-1, merozoite surface protein 1; AMA-1, apical membrane antigen 1.
†Values are % prevalence (no. positive/no. tested) or approximate median titer (IQR) only for seropositive persons unless otherwise indicated.
‡Adjusted for age and correlations between observations from the same household, when applicable.

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