Dengue Virus Surveillance for Early Warning, Singapore
Kim-Sung Lee, Yee-Ling Lai, Sharon Lo, Timothy Barkham, Pauline Aw, Peng-Lim Ooi, Ji-Choong Tai, Martin Hibberd, Patrik Johansson, Seow-Poh Khoo, and Lee-Ching Ng
Author affiliations: Environmental Health Institute, Singapore (K.-S. Lee, Y.-L. Lai, S. Lo, L.-C. Ng); Tan Tock Seng Hospital, Singapore (T. Barkham); Genome Institute of Singapore, Singapore (P. Aw, M. Hibberd); Ministry of Health, Singapore (P.-L. Ooi); National Environment Agency, Singapore (J.-C. Tai, S.-P. Khoo); DSO National Laboratories, Singapore (P. Johansson)
Figure 2. Maximum-likelihood tree showing the phylogenetic relationship of A) dengue virus serotype 2 (DENV-2) and B) DENV-3 from Singapore and global isolates based on the envelope protein gene. EHI, sequence data generated at Environmental Health Institute; new clade, isolates obtained in 2007 and later; old clade, isolates obtained before 2007. Numbers on branches represent bootstrap percentages; only those >80% are shown. Scale bars indicate substitutions per site.
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