Effects of Pneumococcal Conjugate Vaccine 2 Years after Its Introduction, the Netherlands
Gerwin D. Rodenburg1 , Sabine C. de Greeff1, Angelique G.C.S. Jansen, Hester E. de Melker, Leo M. Schouls, Eelko Hak, Lodewijk Spanjaard, Elisabeth A.M. Sanders2, and Arie van der Ende2
Author affiliations: Wilhelmina Children’s Hospital/University Medical Center, Utrecht, the Netherlands (G.D. Rodenburg, A.G.C.S Jansen, E. Hak, E.A.M. Sanders); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (S.C. de Greeff, H.E. de Melker, L.M. Schouls); University Medical Center, Groningen, the Netherlands (E. Hak); Netherlands Reference Laboratory for Bacterial Meningitis, Amsterdam, the Netherlands (L. Spanjaard, A. van der Ende); 1, 2These pairs of authors contributed equally to this study.
Figure 1. Incidence of invasive pneumococcal disease in children <2 years of age in the birth group born after April 1, 2006 (age eligible for 7-valent pneumococcal conjugate vaccine [PCV-7]) and children born before April 1, 2006 (age noneligible for PCV-7), in the postimplementation period compared with age-matched children in the preimplementation period, the Netherlands. Incidence per 100,000 children <2 years of age per year; Pre, preimplementation period (June 2004–June 2006); post, postimplementation period (June 2006–June 2008).
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