Emerging Infectious Disease ISSN: 1080-6059

Effects of Pneumococcal Conjugate Vaccine 2 Years after Its Introduction, the Netherlands

Gerwin D. Rodenburg¹

, Sabine C. de Greeff¹, Angelique G.C.S. Jansen, Hester E. de Melker, Leo M. Schouls, Eelko Hak, Lodewijk Spanjaard, Elisabeth A.M. Sanders², and Arie van der Ende²

Author affiliations: Wilhelmina Children’s Hospital/University Medical Center, Utrecht, the Netherlands (G.D. Rodenburg, A.G.C.S Jansen, E. Hak, E.A.M. Sanders); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (S.C. de Greeff, H.E. de Melker, L.M. Schouls); University Medical Center, Groningen, the Netherlands (E. Hak); Netherlands Reference Laboratory for Bacterial Meningitis, Amsterdam, the Netherlands (L. Spanjaard, A. van der Ende); 1, 2These pairs of authors contributed equally to this study.

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Figure 2

Serotype distribution of invasive pneumococcal disease with regard to preimplementation and postimplementation of 7-valent pneumococcal conjugate vaccine (PCV-7); among persons of all ages, the Netherlands. Preimplementation period June 2004–June 2006; postimplementation period June 2006–June 2008; *p<0.05; proportion of serotypes preimplementation vs. postimplementation period. Calculated using Fisher exact test; all p values are 2 sided.

Figure 2. Serotype distribution of invasive pneumococcal disease with regard to preimplementation and postimplementation of 7-valent pneumococcal conjugate vaccine (PCV-7); among persons of all ages, the Netherlands. Preimplementation period June 2004–June 2006; postimplementation period June 2006–June 2008; *p<0.05; proportion of serotypes preimplementation vs. postimplementation period. Calculated using Fisher exact test; all p values are 2 sided.

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^{1, 2}These pairs of authors contributed equally to this study.

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