Effects of Pneumococcal Conjugate Vaccine 2 Years after Its Introduction, the Netherlands
Gerwin D. Rodenburg1 , Sabine C. de Greeff1, Angelique G.C.S. Jansen, Hester E. de Melker, Leo M. Schouls, Eelko Hak, Lodewijk Spanjaard, Elisabeth A.M. Sanders2, and Arie van der Ende2
Author affiliations: Wilhelmina Children’s Hospital/University Medical Center, Utrecht, the Netherlands (G.D. Rodenburg, A.G.C.S Jansen, E. Hak, E.A.M. Sanders); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (S.C. de Greeff, H.E. de Melker, L.M. Schouls); University Medical Center, Groningen, the Netherlands (E. Hak); Netherlands Reference Laboratory for Bacterial Meningitis, Amsterdam, the Netherlands (L. Spanjaard, A. van der Ende); 1, 2These pairs of authors contributed equally to this study.
Figure 3. Serotype distribution of invasive pneumococcal disease cases among children born after April 1, 2006 (age eligible for 7-valent pneumococcal conjugate vaccine [PCV-7]) in the postimplementation period compared with age-matched children in the preimplementation period, the Netherlands. Preimplementation period, June 2004–June 2006; postimplementation period, June 2006–June 2008; other serotypes are 15A, 16F, 22F, 3, 33F, 5, and 9N. *p<0.05; preimplementation vs. postimplementation periods. Proportions calculated using Fisher exact test; all p values are 2 sided.
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