Emerging Infectious Disease ISSN: 1080-6059

Tropheryma whipplei in Children with Gastroenteritis

Didier Raoult

, Florence Fenollar, Jean-Marc Rolain, Philippe Minodier, Emmanuelle Bosdure, Wenjun Li, Jean-Marc Garnier, and Hervé Richet

Author affiliations: Université de la Méditerranée, Marseille, France (D. Raoult, F. Fenollar, J.-M. Rolain, W. Li, H. Richet); Pôle de Maladies Infectieuses, Marseille (D. Raoult, F. Fenollar, J.-M. Rolain, H. Richet); Hôpital Nord, Marseille (P. Minodier. J.-M Garnier); Hôpital de la Timone, Marseille (E. Bosdure)

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Figure 1

Dendogram constructed by using unweighted pair group method with arithmetic mean and 4 highly variable genomic sequences (HVGS), showing phylogenetic diversity of 48 genotypes of 81 Tropheryma whipplei strains detected in 34 children with diarrhea (blue), 40 adult patients with Whipple disease (red), and 22 asymptomatic adult patients without Whipple disease (green) (including 11 sewer workers), Marseille, France. Sequences were concatenated to construct the dendrogram. Numbers in parentheses in

Figure 1. Dendogram constructed by using unweighted pair group method with arithmetic mean and 4 highly variable genomic sequences (HVGS), showing phylogenetic diversity of 48 genotypes of 81 Tropheryma whipplei strains detected in 34 children with diarrhea (blue), 40 adult patients with Whipple disease (red), and 22 asymptomatic adult patients without Whipple disease (green) (including 11 sewer workers), Marseille, France. Sequences were concatenated to construct the dendrogram. Numbers in parentheses indicate number of genotyped samples for each category. Stars, France; crosses, Switzerland; circles, Germany; diamond, Italy; square, Austria; triangle, Canada; small circle, Comoros.

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