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Volume 16, Number 5—May 2010

Dispatch

Unusual Assortment of Segments in 2 Rare Human Rotavirus Genomes

Simona De GraziaComments to Author , Giovanni M. Giammanco, Christiaan A. Potgieter, Jelle Matthijnssens, Krisztián Bányai, Maria A. Platia, Claudia Colomba, and Vito Martella
Author affiliations: University of Palermo, Palermo, Italy (S. De Grazia, G.M. Giammanco, M.A. Platia, C. Colomba); Ondersterpoort Veterinary Institute, Ondersterpoort, South Africa (C.A. Potgieter); Rega Institute for Medical Research, Leuven, Belgium (J. Matthiinssens); Veterinary Medical Research Institute, Budapest, Hungary (K. Bányai); University of Bari, Valenzano, Italy (V. Martella)

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Table 1

Nucleotide identity of 11 genome segments of 2 human rotavirus strains, Italy, 1994 and 1996*

Gene encoding Cutoff value Genotype of
PAH136/96 Identity of PAH136/96 against indicated strains
Genotype of
PAI58/96 Identity of PAI58/96 against indicated strains
Identity between PAH136/96 and PAI58/96
Prototypes† GenBank strains‡ Prototypes† GenBank strains‡
VP1 83 R2 83.7 (RF) 94.6 (Hun5) R2 94.9 (RF) 95.7 (NCDV) 83.2
VP2 84 C2 90.9 (RF) 98 (Hun5) C2 89.9 (RF) 93.9 (Chubut) 91.6
VP3 81 M2 89.2 (RF) 92.9 (PA169) M2 90.2 (RF) 95.8 (PA169) 92.6
VP4 80 P[9] 95.6 (AU-1) (AU-1) P[9] 95.3 (AU-1) (AU-1) 94.6
VP6 85 I2 86.9 (RF) 95.5 (Hun5) I2 91.8 (RF) 92.4 (UKtc) 86
VP7 80 G3 90.1 (AU-1) 94.2 (Cat2) G3 90.5 (AU-1) 95.9 (Cat2) 95.7
NSP1 79 A3 93.6 (AU-1) 94.8 (Chubut) A3 92.9 (AU-1) 94.1 (Chubut) 92.1
NSP2 85 N1 91.4 (Wa) 99.1 (Cat2) N2 90.1 (RF) 91.4 (NCDV) 79
NSP3 85 T6 94.7 (RF) 97 (MG6) T6 95.9 (RF) (RF) 97.5
NSP4 85 E2 87 (DS-1) 92.5 (PA169) E2 87.5 (DS-1) 98 (PA169) 92.3
NSP5 91 H3 96.8 (RF) 97.3 (111/05) H3 98 (RF) 98.8 (Cat2) 96.3

*Numeric values given as % nt. Percentage nucleotide cutoff values and genotype proposed by Matthijnssens et al. (8). VP, structural protein; NSP, nonstructural protein.
†Prototype genotype strains used by Matthijnssens et al. (8).
‡ Strains that shared the highest nucleotide identity in the cognate genes with the Italian G3P[9] rotaviruses.

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