Volume 16, Number 5—May 2010
Dispatch
Unusual Assortment of Segments in 2 Rare Human Rotavirus Genomes
Simona De Grazia
, Giovanni M. Giammanco, Christiaan A. Potgieter, Jelle Matthijnssens, Krisztián Bányai, Maria A. Platia, Claudia Colomba, and Vito Martella
, Giovanni M. Giammanco, Christiaan A. Potgieter, Jelle Matthijnssens, Krisztián Bányai, Maria A. Platia, Claudia Colomba, and Vito MartellaTable 1
Nucleotide identity of 11 genome segments of 2 human rotavirus strains, Italy, 1994 and 1996*
| Gene encoding | Cutoff value | Genotype of PAH136/96 | Identity of PAH136/96 against indicated strains |
Genotype of PAI58/96 | Identity of PAI58/96 against indicated strains |
Identity between PAH136/96 and PAI58/96 | ||
|---|---|---|---|---|---|---|---|---|
| Prototypes† | GenBank strains‡ | Prototypes† | GenBank strains‡ | |||||
| VP1 | 83 | R2 | 83.7 (RF) | 94.6 (Hun5) | R2 | 94.9 (RF) | 95.7 (NCDV) | 83.2 |
| VP2 | 84 | C2 | 90.9 (RF) | 98 (Hun5) | C2 | 89.9 (RF) | 93.9 (Chubut) | 91.6 |
| VP3 | 81 | M2 | 89.2 (RF) | 92.9 (PA169) | M2 | 90.2 (RF) | 95.8 (PA169) | 92.6 |
| VP4 | 80 | P[9] | 95.6 (AU-1) | (AU-1) | P[9] | 95.3 (AU-1) | (AU-1) | 94.6 |
| VP6 | 85 | I2 | 86.9 (RF) | 95.5 (Hun5) | I2 | 91.8 (RF) | 92.4 (UKtc) | 86 |
| VP7 | 80 | G3 | 90.1 (AU-1) | 94.2 (Cat2) | G3 | 90.5 (AU-1) | 95.9 (Cat2) | 95.7 |
| NSP1 | 79 | A3 | 93.6 (AU-1) | 94.8 (Chubut) | A3 | 92.9 (AU-1) | 94.1 (Chubut) | 92.1 |
| NSP2 | 85 | N1 | 91.4 (Wa) | 99.1 (Cat2) | N2 | 90.1 (RF) | 91.4 (NCDV) | 79 |
| NSP3 | 85 | T6 | 94.7 (RF) | 97 (MG6) | T6 | 95.9 (RF) | (RF) | 97.5 |
| NSP4 | 85 | E2 | 87 (DS-1) | 92.5 (PA169) | E2 | 87.5 (DS-1) | 98 (PA169) | 92.3 |
| NSP5 | 91 | H3 | 96.8 (RF) | 97.3 (111/05) | H3 | 98 (RF) | 98.8 (Cat2) | 96.3 |
*Numeric values given as % nt. Percentage nucleotide cutoff values and genotype proposed by Matthijnssens et al. (8). VP, structural protein; NSP, nonstructural protein.
†Prototype genotype strains used by Matthijnssens et al. (8).
‡ Strains that shared the highest nucleotide identity in the cognate genes with the Italian G3P[9] rotaviruses.
