Rhinovirus C and Respiratory Exacerbations in Children with Cystic Fibrosis
Marina B. de Almeida , Rodrigo M. Zerbinati, Adriana F. Tateno, Cristina M. Oliveira, Renata M. Romão, Joaquim C. Rodrigues, Cláudio S. Pannuti, and Luiz Vicente F. da Silva Filho
Author affiliations: Hospital das Clínicas da Faculdade de Medicina de Universidade de São Paulo, São Paulo, Brazil (M.B. de Almeida, J.C. Rodrigues, L.V.F. da Silva Filho); Universidade de São Paulo, São Paulo (R.M. Zerbinati, A.F. Tateno, C.M. Oliveira, R.M. Romão, C.S. Pannuti, L.V.F. da Silva Filho)
Figure 2. Representative maximum-likelihood phylogenetic tree of a partial 5′ noncoding region of human rhinovirus generated with general time reversible substitution model, including gamma distribution shape parameter. Reference human rhinovirus (HRV) genotypes were obtained from the GenBank database. Echovirus 11 was defined as the outgroup. Virus isolates obtained in this study are indicated by boldface and are labeled VFC. Bootstrap values >70% in the key branches are depicted. Scale bar indicates nucleotide substitutions per site.
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