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Volume 17, Number 10—October 2011

CME ACTIVITY

Invasive Non-Aspergillus Mold Infections in Transplant Recipients, United States, 2001–2006

Earning Medscape CME Credit

To obtain credit, you should first read the journal article. After reading the article, you should be able to answer the following, related, multiple-choice questions. To complete the questions (with a minimum 70% passing score) and earn continuing medical education (CME) credit, please go to www.medscape.org/journal/eid. Credit cannot be obtained for tests completed on paper, although you may use the worksheet below to keep a record of your answers. You must be a registered user on Medscape.org. If you are not registered on Medscape.org, please click on the New Users: Free Registration link on the left hand side of the website to register. Only one answer is correct for each question. Once you successfully answer all post-test questions you will be able to view and/or print your certificate. For questions regarding the content of this activity, contact the accredited provider, CME@medscape.net. For technical assistance, contact CME@webmd.net. American Medical Association’s Physician’s Recognition Award (AMA PRA) credits are accepted in the US as evidence of participation in CME activities. For further information on this award, please refer to http://www.ama-assn.org/ama/pub/category/2922.html. The AMA has determined that physicians not licensed in the US who participate in this CME activity are eligible for AMA PRA Category 1 Credits™. Through agreements that the AMA has made with agencies in some countries, AMA PRA credit may be acceptable as evidence of participation in CME activities. If you are not licensed in the US, please complete the questions online, print the certificate and present it to your national medical association for review.

Article Title: Invasive Non-Aspergillus Mold Infections in Transplant Recipients, United States, 2001–2006

CME Questions

1. You are preparing a 35-year-old woman for hematopoietic cell transplantation (HCT) from a related donor, and you are concerned with the possibility of a fungal infection following transplantation. Which of the following infections was most common among the current cohort of transplant recipients?

A. Scedosporiosis

B. Mucormycosis

C. Chromoblastomycosis

D. Fusariosis

2. Which of the following statements regarding patient characteristics of individuals with fungal infection in the current study is most accurate?

A. All cases had proven invasive fungal infection

B. The overall 90-day mortality rate exceeded 50%

C. Nearly all patients had neutropenia before fungal infection

D. The prevalence of mucormycosis was highest among recipients of HCT from allogenic human leukocyte antigen mismatched related donors

3. What else should you consider regarding factors associated with fungal infection in the current study?

A. Most mold infections occurred in the gastrointestinal tract

B. Liver transplant was particularly associated with a higher risk for mucormycosis

C. There were no cases of late-onset infection

D. Voriconazole failed to prevent many infections, especially mucormycosis

4. Which of the following statements regarding mucormycosis in the current study is most accurate?

A. Rhizopus was the most common genus

B. Renal transplants were associated with the highest incidence of mucormycosis

C. The annual incidence rates of mucormycosis remained stable during the study period

D. Mucormycosis was most common in the months from January to April

Activity Evaluation

1. The activity supported the learning objectives.

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2. The material was organized clearly for learning to occur.

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3. The content learned from this activity will impact my practice.

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4. The activity was presented objectively and free of commercial bias.

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