Volume 17, Number 10—October 2011
Dispatch
Extensively Drug-Resistant Tuberculosis in Women, KwaZulu-Natal, South Africa
Max R. O’Donnell
, Jennifer Zelnick, Lise Werner, Iqbal Master, Marian Loveday, C. Robert Horsburgh, and Nesri Padayatchi
, Jennifer Zelnick, Lise Werner, Iqbal Master, Marian Loveday, C. Robert Horsburgh, and Nesri PadayatchiTable 1
Characteristics of 4,514 adults >18 years of age with MDR TB and XDR TB admitted to King George V Hospital, KwaZulu-Natal, South Africa, 2003–2008*
| Characteristic† | No. (%) women, n = 2,208 | No. (%) men, n = 2,306 | p value |
|---|---|---|---|
| HIV status | |||
| Positive | 1,431 (64.8) | 1,083 (47.0) | <0.0001 |
| Negative | 394 (17.8) | 642 (27.8) | |
| Unknown | 383 (17.3) | 581 (25.2) | |
| HIV positive and ART | |||
| Yes | 731 (51.1) | 465 (42.9) | <0.0001 |
| No | 700 (48.9) | 618 (57.1) | |
| Health care worker | |||
| Yes | 180 (8.2) | 51 (2.2) | <0.0001 |
| No | 2,028 (91.8) | 2,255 (97.8) | |
| Previous treatment | |||
| Yes | 1,987 (95.4) | 2,127 (94.4) | 0.1305 |
| No | 96 (4.6) | 127 (5.6) | |
| Year of hospital admission | |||
| 2003 | 188 (8.5) | 278 (12.1) | 0.0011‡ |
| 2004 | 195 (8.8) | 234 (10.1) | |
| 2005 | 272 (12.3) | 283 (12.3) | |
| 2006 | 358 (16.2) | 350 (15.2) | |
| 2007 | 590 (26.7) | 593 (25.7) | |
| 2008 | 605 (27.4) | 568 (24.6) | |
| Type of TB | |||
| MDR | 1,987 (90.0) | 2,150 (93.2) | <0.0001 |
| XDR | 221 (10.0) | 156 (6.8) |
*MDR, multidrug-resistant; TB, tuberculosis; XDR, extensively drug-resistant; ART, antiretroviral therapy. |
*MDR, multidrug-resistant; TB, tuberculosis; XDR, extensively drug-resistant; ART, antiretroviral therapy.
†Median patient age (interquartile range): women, 32 y (26–39 y); men, 36 y (30–44 y); p<0.0001.
‡Cochran-Armitage test for trend.
