Volume 17, Number 10—October 2011
Research
Multidrug-Resistant Tuberculosis, People’s Republic of China, 2007–2009
Guang Xue He1
, Hai Ying Wang1, Martien W. Borgdorff, Dick van Soolingen, Marieke J. van der Werf, Zhi Min Liu, Xue Zheng Li, Hui Guo, Yan Lin Zhao, Jay K. Varma, Christopher P. Tostado, and Susan van den Hof
, Hai Ying Wang1, Martien W. Borgdorff, Dick van Soolingen, Marieke J. van der Werf, Zhi Min Liu, Xue Zheng Li, Hui Guo, Yan Lin Zhao, Jay K. Varma, Christopher P. Tostado, and Susan van den HofTable 2
Risk factors for MDR TB, Shandong Province, People’s Republic of China, April 2007–July 2009*
| Patient data | No. (%) patients with MDR TB, n = 100 | No. (%) patients with pan-sensitive TB, n = 97 | Crude OR (95% CI) | Adjusted OR† (95% CI) |
|---|---|---|---|---|
| Sex | ||||
| M | 61 (61.0) | 67 (69.1) | 1 | |
| F |
39 (39.0) |
30 (30.9) |
0.7 (0.4–1.3) |
|
| Age group, y | ||||
| 15–34 | 49 (49.0) | 56 (57.7) | 1 | |
| 35–54 | 38 (38.0) | 21 (21.6) | 2.1 (1.1–4.0) | |
| >55 |
13 (13.0) |
20 (20.6) |
0.7 (0.3–1.6) |
|
| Occupation | ||||
| Farmer | 39 (39.0) | 29 (29.9) | 1 | 1 |
| Blue-collar worker | 16 (16.0) | 12 (12.4) | 1.0 (0.4–2.4) | 0.8 (0.2–2.4) |
| White-collar worker | 37 (37.0) | 39 (40.2) | 0.7 (0.4–1.4) | 0.6 (0.3–1.4) |
| Student |
8 (8.0) |
17 (17.5) |
0.4 (0.1–0.9) |
0.2 (0.1–0.7) |
| Close contact with TB patient | ||||
| No | 90 (90.0) | 90 (92.8) | 1 | |
| Yes |
10 (10.0) |
7 (7.2) |
0.7 (0.3–1.9) |
|
| Health insurance | ||||
| Yes | 33 (33.0) | 48 (49.5) | 1 | 1 |
| No |
67 (67.0) |
49 (50.5) |
2.0 (1.1–3.5) |
2.4 (1.1–5.1) |
| History of TB treatment | ||||
| New case | 45 (45.0) | 90 (92.8) | 1 | 1 |
| Retreatment case |
55 (55.0) |
7 (7.2) |
15.7 (6.6–37.3) |
12.0 (4.5–31.8) |
| Symptom duration before first evaluation in Shandong Provincial TB Hospital, mo | ||||
| <1 | 14 (14.0) | 31 (32.0) | 1 | 1 |
| 1–2 | 16 (16.0) | 30 (30.9) | 1.2 (0.5–2.8) | 1.3 (0.5–3.8) |
| 3–5 | 14 (14.0) | 17 (17.5) | 1.8 (0.7–4.7) | 3.0 (1.0–9.2) |
| >6 |
56 (56.0) |
19 (19.6) |
6.5 (2.9–14.8) |
3.3 (1.2–9.1) |
| Cavity visible on radiograph | ||||
| No | 55 (55.0) | 67 (69.1) | 1 | |
| Yes |
45 (45.0) |
30 (30.9) |
1.8 (1.0–3.3) |
|
| Beijing genotype | ||||
| No | 6 (6.0) | 20 (20.6) | 1 | 1 |
| Yes | 94 (94.0) | 77 (79.4) | 4.1 (1.6–10.6) | 4.3 (1.4–13.9) |
*MDR TB, multidrug-resistant tuberculosis; OR, odds ratio; CI, confidence interval.
†Adjusted for all other factors included in the multivariate model.
1These authors contributed equally to this article.
