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Volume 17, Number 10—October 2011

Research

Multidrug-Resistant Tuberculosis, People’s Republic of China, 2007–2009

Guang Xue He1Comments to Author , Hai Ying Wang1, Martien W. Borgdorff, Dick van Soolingen, Marieke J. van der Werf, Zhi Min Liu, Xue Zheng Li, Hui Guo, Yan Lin Zhao, Jay K. Varma, Christopher P. Tostado, and Susan van den Hof

Author affiliations: Chinese Center for Disease Control and Prevention, Beijing, People’s Republic of China (G.X. He, H. Guo, Y.L. Zhao); University of Amsterdam, Amsterdam, the Netherlands (G.X. He, M.W. Borgdorff, M.J. van der Werf, S. van den Hof); Shandong Provincial Tuberculosis Control Center, Jinan, People’s Republic of China (H.Y. Wang, Z.M. Liu, X.Z. Li); National Institute for Public Health and the Environment, Bilthoven, the Netherlands (D. van Soolingen); KNCV Tuberculosis Foundation, The Hague, the Netherlands (M.J. van der Werf, S. van den Hof); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (J.K. Varma); Tsinghua University, Beijing (C.P. Tostado)

Main Article

Table 2

Risk factors for MDR TB, Shandong Province, People’s Republic of China, April 2007–July 2009*

Patient data No. (%) patients with MDR TB, n = 100 No. (%) patients with pan-sensitive TB, n = 97 Crude OR (95% CI) Adjusted OR† (95% CI)
Sex
M 61 (61.0) 67 (69.1) 1
F
39 (39.0)
30 (30.9)
0.7 (0.4–1.3)

Age group, y
15–34 49 (49.0) 56 (57.7) 1
35–54 38 (38.0) 21 (21.6) 2.1 (1.1–4.0)
>55
13 (13.0)
20 (20.6)
0.7 (0.3–1.6)

Occupation
Farmer 39 (39.0) 29 (29.9) 1 1
Blue-collar worker 16 (16.0) 12 (12.4) 1.0 (0.4–2.4) 0.8 (0.2–2.4)
White-collar worker 37 (37.0) 39 (40.2) 0.7 (0.4–1.4) 0.6 (0.3–1.4)
Student
8 (8.0)
17 (17.5)
0.4 (0.1–0.9)
0.2 (0.1–0.7)
Close contact with TB patient
No 90 (90.0) 90 (92.8) 1
Yes
10 (10.0)
7 (7.2)
0.7 (0.3–1.9)

Health insurance
Yes 33 (33.0) 48 (49.5) 1 1
No
67 (67.0)
49 (50.5)
2.0 (1.1–3.5)
2.4 (1.1–5.1)
History of TB treatment
New case 45 (45.0) 90 (92.8) 1 1
Retreatment case
55 (55.0)
7 (7.2)
15.7 (6.6–37.3)
12.0 (4.5–31.8)
Symptom duration before first evaluation in Shandong Provincial TB Hospital, mo
<1 14 (14.0) 31 (32.0) 1 1
1–2 16 (16.0) 30 (30.9) 1.2 (0.5–2.8) 1.3 (0.5–3.8)
3–5 14 (14.0) 17 (17.5) 1.8 (0.7–4.7) 3.0 (1.0–9.2)
>6
56 (56.0)
19 (19.6)
6.5 (2.9–14.8)
3.3 (1.2–9.1)
Cavity visible on radiograph
No 55 (55.0) 67 (69.1) 1
Yes
45 (45.0)
30 (30.9)
1.8 (1.0–3.3)

Beijing genotype
No 6 (6.0) 20 (20.6) 1 1
Yes 94 (94.0) 77 (79.4) 4.1 (1.6–10.6) 4.3 (1.4–13.9)

*MDR TB, multidrug-resistant tuberculosis; OR, odds ratio; CI, confidence interval.
†Adjusted for all other factors included in the multivariate model.

Main Article

1These authors contributed equally to this article.

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