Emerging Infectious Disease ISSN: 1080-6059

Hepatitis E Virus in Rats, Los Angeles, California, USA

Robert H. Purcell, Ronald E. Engle, Michael P. Rood, Yamina Kabrane-Lazizi¹, Hanh T. Nguyen, Sugantha Govindarajan, Marisa St. Claire², and Suzanne U. Emerson

Author affiliations: National Institutes of Health, Bethesda Maryland, USA (R.H. Purcell, R.E. Engle, Y. Kabrane-Lazizi, H.T. Nguyen, S.U. Emerson); Department of Public Health Services, Los Angeles, California, USA (M.P. Rood); Rancho Los Amigos Hospital, Downey, California, USA (S. Govindarajan); Bioqual, Inc., Rockville, Maryland, USA (M. St. Claire)

Main Article

Figure 2

Correlation between virus infection and serum levels of alanine aminotransferase (ALT) (shaded areas) in rats infected with hepatitis E virus, Los Angeles, California, USA. Six Sprague-Dawley rats (B430–5) were infected with a 104.5 50% rat infectious dose of rat HEV and tested 2×/wk for evidence of infection and hepatitis. PCR results were positive for only half a week in 5 of the 6 rats. Pre, preinfection.

Figure 2. Correlation between virus infection and serum levels of alanine aminotransferase (ALT) (shaded areas) in rats infected with hepatitis E virus, Los Angeles, California, USA. Six Sprague-Dawley rats (B430–5) were infected with a 10^4.5 50% rat infectious dose of rat HEV and tested 2×/wk for evidence of infection and hepatitis. PCR results were positive for only half a week in 5 of the 6 rats. Pre, preinfection.

Main Article

¹Current affiliation: Embassy of France, Beijing, People’s Republic of China.

²Current affiliation: National Institutes of Health, Frederick, Maryland, USA.

Top of Page

The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.