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Volume 17, Number 2—February 2011

Dispatch

Pandemic (H1N1) 2009–associated Pneumonia in Children, Japan

Maki Hasegawa, Takafumi Okada, Hiroshi Sakata, Eiichi Nakayama, Tatsuo Fuchigami, Yasuji Inamo, Hideo Mugishima, Takeshi Tajima, Satoshi Iwata, Miyuki Morozumi, Kimiko Ubukata, Haruo Watanabe, and Takashi TakahashiComments to Author 
Author affiliations: Author affiliations: Kitasato University, Tokyo (M. Hasegawa, T. Okada, E. Nakayama, M. Morozumi, K. Ubukata, T. Takahashi); Nihon University School of Medicine, Tokyo, Japan (M. Hasegawa, T. Fuchigami, Y. Inamo, H. Mugishima); National Hospital Organization Tokyo Medical Center, Tokyo (T. Okada, S. Iwata); Asahikawa-Kosei General Hospital, Asahikawa, Japan (H. Sakata); Komagome Hospital, Tokyo (E. Nakayama); Hakujikai Memorial Hospital, Tokyo (T. Tajima); National Institute of Infectious Diseases, Tokyo (H. Watanabe)

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Table 2

Laboratory test results for children hospitalized with pandemic (H1N1) 2009–associated pneumonia, Japan, August–November 2009*

Characteristic Group A, no complications, n = 63
Group B, complications, n = 17
Age <5 y, n = 15 Age >6 y, n = 48 Age >6 y, n = 14
Leukocytes, cells/μL (range)† 6,400 (3,600–14,400) 7,400 (2,400–17,100) 14,200 (5,100–22,700)
Neutrophils‡ 4,929 (2,227–8,256) 6,081(1,248–15,287) 12,849 (4,182–22,042)
Lymphocytes§ 1,593 (74–7,638) 608 (214–2,064) 560 (295–1,889)
Eosinophils 0 (0–102) 16 (0–918) 23 (0–145)
Monocytes
240 (37–1,685)
359 (99–1,271)

337 (0–714)
CRP, mg/dL (range)¶ 1.0 (0.1–2.9) 2.4 (0.05–11.95) 3.5 (1–7.83)
LDH, IU/L (range)¶ 304 (230–415) 248 (182–575) 248 (193–353)
CK, IU/L (range)¶ 101 (40–328) 110 (29–2,240) 148 (57–1,524)
IgE, IU/mL (range)# 61 (7.3–311) 443 (34–4,680) 1,058 (43–4,011)

*CRP, C-reactive protein; LDH, lactate dehydrogenase; CK, creatine kinase; Ig, immunoglobulin.
†Reference ranges by age group: <1 y, 7,000–15,000; 2–5 y, 7,000–11,000; >6 y, 6,500–10,000.
‡Reference range by age group: <1 y, 4,000–8,000; 2–5 y, 2,500–5,500; >6 y, 3,000–5,000.
§Reference range by age group: <1 y, 4,000–11,000; 2–5 y, 3,000–7,000; >6 y, 2,500–4,500.
¶Reference upper limits for CRP, LDH, and CK levels are 0.3, 400, and 200, respectively.
#Reference ranges for IgE by age group: 1–3 y, <30; 4–6 y, <110; >7 y, <170. Serum IgE data were analyzed when available.

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