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Volume 17, Number 2—February 2011

Research

Severe Cases of Pandemic (H1N1) 2009 in Children, Germany

Mathias AltmannComments to Author , Lena Fiebig, Jana Soyka, Rüdiger von Kries, Manuel Dehnert, and Walter Haas
Author affiliations: Author affiliations: Robert Koch Institute, Berlin, Germany (M. Altmann, L. Fiebig, J. Soyka, M. Dehnert, W. Haas); Ludwig-Maximilians-Universität, Munich, Germany (R. von Kries)

Main Article

Table 3

Clinical course for children with severe pandemic (H1N1) 2009, Germany, 2009–2010*

Characteristic Total Nonsurvivors not in PICU Admitted to PICU
Survivors Nonsurvivors Subtotal p value
Time course of illness, d
Symptom to hospital admission 77, 2 (1–5) 3, 1 (1–2) 65, 2 (1–5) 9, 1 (1–3) 74, 2 (1–5) 0.700
Hospitalization to PICU
admission 74, 0 (0–1) NA 65, 0 (0–1) 9, 1 (0–3) 74, 0 (0–1) 0.236
PICU length of stay 80, 8 (3–17) NA 69, 9 (3–18) 11, 2 (0–8) 80, 8 (3–17) NC
Hospital length of stay 83, 14 (5–23) 3, 5 (3–12) 69, 16 (7–25) 11, 3 (2–12) 80, 14.5 (5.5–23.5) NC
Symptom onset to outcome†
85, 16 (8–26)
4, 5.5 (5–9.5)
72, 18.5 (10.5–29.5)
9, 8 (3–12)
81, 17 (8–27)
NC
Time to treatment, d
Symptom onset to oseltamivir
treatment 45, 4 (1–7) 1, 4‡ 39, 4 (1–7) 5, 4 (2–8) 44, 4 (1–7) 0.551

*Values given are total no. with available information, median (IQR) ,except as indicated. PICU, pediatric intensive care unit; IQR, interquartile range; NA, not applicable (not admitted to PICU); NC, not compared because of different outcomes (release for survivors and death for nonsurvivors).
†Including patients with hospital-acquired pandemic (H1N1) 2009 infection.
‡Only 1 observation.

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