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Volume 17, Number 4—April 2011


Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010

Joanne E. EnstoneComments to Author , Puja R. Myles, Peter J.M. Openshaw, Elaine M. Gadd, Wei Shen Lim, Malcolm G. Semple, Robert C. Read, Bruce L. Taylor, James McMenamin, Colin Armstrong, Barbara Bannister, Karl G. Nicholson, and Jonathan S. Nguyen-Van-Tam
Author affiliations: Author affiliations: University of Nottingham, Nottingham, UK (J.E. Enstone, P.R. Myles, J.S. Nguyen-Van-Tam); Imperial College, London, UK (P.J.M. Openshaw); Department of Health, London (E.M. Gadd, C. Armstrong, B. Bannister); Nottingham University Hospitals National Health Service Trust, Nottingham (W.S. Lim); University of Liverpool, Liverpool, UK (M.G. Semple); University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK (R.C. Read); Portsmouth Hospitals National Health Service Trust, Portsmouth, UK (B.L. Taylor); Health Protection Scotland, Glasgow, Scotland (J. McMenamin); University Hospitals of Leicester National Health Service Trust, Leicester, UK (K.G. Nicholson)

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Table 2

Timelines and outcomes for 15 hospitalized adults with nosocomial pandemic (H1N1) 2009, United Kingdom, 2009–2010

Patient no. Age, y/sex Duration, d
Maximum level of care* Outcome†
Hospital admission to symptom onset Symptom onset to receipt of antiviral therapy
1 51/F 26 0 0/1 Unknown data
2 44/M 14 0 0/1 Recovered
3 34/M 8 0 3 Died
4 18/F 4 Not given 2 Transferred to other hospital
5 48/M 9 4 0/1 Recovered
6 43/M 5 0 0/1 Recovered
7 51/M 29 0 3 Died
8 39/F 5 3 0/1 Died
9 76/M 11 Not given 3 Died
10 45/F 24 2 0/1 Recovered
11 44/F 14 Not given 3 Transferred, improved
12 22/M 5 0 3 Died
13 52/M 78 1‡ 3 Recovered
14 33/F 7 3 0/1 Recovered
15 60/M 13 Not given 3 Recovered

*Level 0 care is given to patients whose care needs can be met through normal ward care. Level 1 care is given to patients at risk for a deteriorating condition or recently relocated from higher levels of care whose needs can be met in an acute-care ward with additional advice and support from the critical-care team. Level 3 care is given to patients requiring advanced respiratory support alone or basic respiratory support and support for >2 organ systems; this level includes all patients with complex conditions that required support for multiorgan failure (intensive care unit). Level 2 care is given to patients requiring more detailed observation or intervention, including support for a single failing organ system and those changing from higher levels of care (high dependency unit).
†Deaths were attributed to pandemic (H1N1) 2009.
‡Oseltamivir was replaced with zanamivir on day 5 because of identification of the H275Y drug-resistance mutation.

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