Emerging Infectious Disease ISSN: 1080-6059

Use of Antiviral Drugs to Reduce Household Transmission of Pandemic (H1N1) 2009, United Kingdom1

Richard G. Pebody

, Ross Harris, George Kafatos, Mary Chamberland, Colin Campbell, Jonathan S. Nguyen-Van-Tam, Estelle McLean, Nick Andrews, Peter J. White, Edward Wynne-Evans, Jon Green, Joanna Ellis, Tim Wreghitt, Sam Bracebridge, Chikwe Ihekweazu, Isabel Oliver, Gillian Smith, Colin Hawkins, Roland Salmon, Brian Smyth, Jim McMenamin, Maria Zambon, Nick F. Phin, and John M. Watson

Author affiliations: Author affiliations: Health Protection Agency, London, UK (R.G. Pebody, R. Harris, G. Kafatos, M. Chamberland, C. Campbell, J.S. Nguyen-Van-Tam, E. McLean, N. Andrews, P.J. White, E. Wynne-Evans, J. Green, J. Ellis, T. Wreghitt, S. Bracebridge, C. Ihekweazu, I. Oliver, G. Smith, C. Hawkins, M. Zambon, N. Phin, J.M. Watson); Imperial College, London (P.J. White); Public Health Wales, Cardiff, Wales, UK (R. Salmon); Public Health Agency Northern Ireland, Belfast, Northern Ireland (B. Smyth); Health Protection Scotland, Glasgow, Scotland (J. McMenamin)

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Figure 1

Flowchart of pandemic (H1N1) 2009 case-patients and household contacts, including contacts with respiratory symptoms, contacts from whom swab specimens were collected, and PCR result, United Kingdom, 2009. *Symptom onset date <2 weeks after index case-patient symptom onset; †46 persons had symptom onset date >2 weeks after index case-patient and 4 had missing symptom onset date; ‡5 persons had swabs taken >2 weeks after index case-patient symptom onset, and 3 had positive test results;

Figure 1. Flowchart of pandemic (H1N1) 2009 case-patients and household contacts, including contacts with respiratory symptoms, contacts from whom swab specimens were collected, and PCR result, United Kingdom, 2009. *Symptom onset date <2 weeks after index case-patient symptom onset; †46 persons had symptom onset date >2 weeks after index case-patient and 4 had missing symptom onset date; ‡5 persons had swabs taken >2 weeks after index case-patient symptom onset, and 3 had positive test results; §2 persons (neither positive) had swabs taken >2 weeks after index case-patient symptom onset; ¶3 persons (none positive) had swabs taken >2 weeks after index case-patient symptom onset.

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¹Elements of this work were presented at the Health Protection Agency Annual Conference in 2009. An abstract was presented at the International Conference on Emerging Infectious Diseases, Atlanta, Georgia, USA, 2010.

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