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Volume 17, Number 7—July 2011

Dispatch

Melioidosis, Phnom Penh, Cambodia

Erika VliegheComments to Author , Lim Kruy, Birgit De Smet, Chun Kham, Chhun Heng Veng, Thong Phe, Olivier Koole, Sopheak Thai, Lut Lynen, and Jan Jacobs
Author affiliations: Author affiliations: Institute of Tropical Medicine, Antwerp, Belgium (E. Vlieghe, B. DeSmet, O. Koole, L. Lynen, J. Jacobs); Sihanouk Hospital Centre of Hope Phnom Penh, Cambodia (L. Kruy, C. Kham, C.H. Veng, T. Phe, S. Thai)

Main Article

Table 2

Predictors of death for 55 patients with melioidosis, Phnom Penh, Cambodia, July 1, 2007–January 31, 2010*

Risk factor Presence of risk factor No. patients No. patients who died Relative risk (95% CI) p value
Age >55 y Y 24 14 1.13 (0.70–1.83) 0.786

N
31
16


Male sex Y 31 18 1.16 (0.70–1.91) 0.595

N
24
12


Rainy season Y 36 23 1.73 (0.92–3.28) 0.087

N
19
7


Diabetes Y 32 14 0.70 (0.41–1.21) 0.359

N
16
10


Alcoholism Y 7 6 0.97 (1.19–3.22) 0.092

N
32
14


Clinical sign
Duration of symptoms <2 mo Y 12 3 2.26 (0.80–6.42) 0.152
N 23 13
Bloodstream infection Y 37 28 6.81 (1.82–25.50) <0.001
N 18 2
Pneumonia Y 28 18 1.52 (0.90–2.57) 0.172
N 26 11
Deep abscesses Y 15 6 0.80 (0.38–1.67) 0.742
N 24 12
Bone/joint infection Y 8 4 1.04 (0.47–2.28) 1.000
N 29 14
Urogenital infection Y 5 1 0.38 (0.64–2.25) 0.345
N 38 20
Skin and soft tissue infection Y 19 6 0.48 (0.24–0.97) 0.023
N 35 23
Shock or multiorgan failure Y 17 13 4.59 (1.60–13.32) <0.001

N
18
3


Therapy
Inappropriate empiric therapy Y 18 18 3.50 (2.07–5.90) <0.001
N 35 10

*Not all information about outcome predictors was available from all patients. Fisher exact test was used for categorical variables and Student t test for continuous variables. CI, confidence interval. Statistically significant associations (p<0.05) are shown in boldface.

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