Volume 17, Number 9—September 2011
Letter
Highly Virulent Escherichia coli O26, Scotland
Kevin G.J. Pollock
, Sheetal Bhojani, T. James Beattie, Lesley Allison, Mary Hanson, Mary E. Locking, and John M. Cowden
, Sheetal Bhojani, T. James Beattie, Lesley Allison, Mary Hanson, Mary E. Locking, and John M. CowdenTable
Characteristics of infection in children with Escherichia coli O157 versus E. coli O26, Scotland, 2010*
| Variable | O157 HUS, n = 12 | O26 HUS, n = 3 | p value |
|---|---|---|---|
| Age, y |
4.5 ± 1.0 |
3.7 ± 1.3 |
|
| Clinical signs and symptoms | |||
| Diarrhea | 12 | 3 | |
| Bloody diarrhea | 8 (67) | 2 (67) | NS |
| Abdominal pain | 8 (67) | 3 (75) | NS |
| Fever | 2 (17) | 1 (33) | NS |
| Neurologic involvement | 3 (25) | 3 (100) | 0.02 |
| Diabetes | 1 (12) | 2 (67) | 0.02 |
| Cardiomyopathy | 0 | 1 (33) | 0.04 |
| Anuria, d |
7.7 ± 2.4 |
15.7 ± 1.3 |
0.04 |
| Clinical parameters | |||
| Leukocyte count × 109/L | 42.1 ± 14.4 | 25.9 ± 4.8 | NS |
| C-reactive protein, mg/L | 93.5 ± 28.4 | 151 ± 74 | NS |
| Serum albumin, g/L | 22.5 ± 1.3 | 22.3 ± 2.4 | NS |
| Lactate dehydrogenase, IU/L |
2,521 ± 362 |
1,991 ± 642 |
NS |
| Admission to ITU | 3 (25) | 3 (100) | 0.04 |
| Duration of hospitalization, d |
13.2 ± 2.2 |
25 ± 3.8 |
0.03 |
| Treatment | |||
| Peritoneal dialysis, d | 7.4 ± 1.9 | 10 | NS |
| Hemodialysis, d | 8.5 ± 1.5 | 8.3 ± 3.0 | NS |
| Hemofiltration | 0 | 3 (100) | 0.001 |
| Laparotomy |
0 |
1 (33) |
0.04 |
| Postdischarge hypertension | 0 | 2 (67) | 0.01 |
*Values are mean ± SE or no. (%). Significance relates to difference between groups. HUS, hemolytic uremic syndrome; NS, not significant, ITU, intensive treatment unit.
