Temperate Climate Niche for Cryptococcus gattii in Northern Europe
Anuradha Chowdhary, Harbans S. Randhawa, Teun Boekhout, Ferry Hagen, Corné H. Klaassen, and Jacques F. Meis
Author affiliations: University of Delhi, Delhi, India (A. Chowdhary, H.S. Randhawa); Centraalbureau voor Schimmelcultures Fungal Biodiversity Center, Utrecht, the Netherlands (T. Boekhout); Canisius Wilhelmina Hospital, Nijmegen, the Netherlands (F. Hagen, C.H. Klaassen, J.F. Meis); Radboud University Nijmegen Medical Centre, Nijmegen (J.F. Meis)
Figure. Unrooted bootstrap maximum-likelihood phylogenetic multilocus sequence typing analysis of Cryptococcus gattii genotype AFLP4/VGI isolates based on 7 unlinked nuclear loci (5). Red indicates the 3 C. gattii isolates from the Netherlands cultured from Douglas fir (Pseudotsuga menziesii) (CBS12349, CBS12355, CBS12356) and 1 clinical isolate from 1957 from the Netherlands (CBS2502) (6). Green indicates the previously observed European Mediterranean cluster, with clinical, animal and environmental isolates (3). All other C. gattii AFLP4/VGI isolates originate mainly from Australia, Africa, and South America, as described (5). The isolates from the Netherlands are closely related to isolates that originated from the Mediterranean region. Numbers next to branches show bootstrap support (>80).
The opinions expressed by authors contributing to this journal do not necessarily reflect the opinions of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.