Volume 18, Number 12—December 2012
Dispatch
West Nile Virus Neurologic Disease in Humans, South Africa, September 2008–May 2009
Dewald Zaayman and Marietjie Venter
Table 1
Characteristics and clinical information for 7 acutely ill patients with WNV infection, South Africa*
| Sample no. | Date sample collected | Patient age, y/sex | Sample type | WNV antigen/antibody test |
Clinical information | ||
|---|---|---|---|---|---|---|---|
| AN (titer) | IgM | PCR | |||||
| 4562 | 2008 Nov | 45/M | CSF | Pos (4) | – | – | Suspected HIV encephalopathy or PML, TPHA neg, HIV neg, paraparesis |
| 6208 | 2008 Nov | 35/F | CSF | Pos (4) | – | – | Hepatomegaly, lymphadenopathy, fever, vomiting, epigastric pain, EBV IgM neg, EBV IgG pos, malaria neg, hepatitis neg |
| 8785 | 2009 Jan | 36/M | CSF | Pos (4) | – | – | Acute paresis of lower limbs, delirium, HSV-1 and HSV-2 neg (PCR), HTLV-1 neg, TPHA neg |
| 3111 | 2009 Feb | 5/M | CSF | Pos (4) | – | – | Meningitis, enterovirus pos (PCR) |
| 0269 | 2009 Apr | 11/M | Serum | Pos (40) | Pos | Neg | Rash, fever, Brucella neg (PCR), coxsackieviruses B1–B6 neg, CMV IgM neg, CMV IgG pos |
| 0312 | 2009 Apr | 26/M | Serum | Pos (80) | Pos | Neg | Severe headache, fever, suspected enterovirus, coxsackieviruses B1–B5 neg, Rickettsia conorii neg, EBV IgM neg |
| SAH 5238 | 2008 Oct | 2/M | CSF | Neg | Neg | Pos | Decreased level of consciousness, rash, fever, meningitis, measles neg, mumps neg |
*WNV, West Nile virus; AN, antibody neutralization; CSF, cerebrospinal fluid; pos, positive; –, insufficient sample for testing; PML, progressive multifocal leukoencephalopathy; TPHA, Treponema pallidum hemagglutination assay; neg, negative; EBV, Epstein-Barr virus; HSV-1 and -2, herpes simplex virus types 1 and 2; HTLV, human T-lymphotropic virus; CMV, cytomegalovirus.
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Page updated: November 20, 2012
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