Figure 1. . Timeline of 2011 vaccinia virus (VACV) outbreak in Serro County, Minas Gerais state, southeastern Brazil, involving 2 neighboring farms, 91 dairy cattle, and 3 dairy farm workers. Day 1, first case of bovine vaccinia in cow, farm 1; day 3, first case of human infection, patient 1, farm 1; day 5, more cases in cattle, farm 1; day 7, entire herd of cattle sick, farm 1; day 9, first 6 cows sick, farm 2; day 12, second and third human cases (patients B and C); day 15, patient C hospitalized; day 18, entire herd of cattle sick, farm 2; day 22, cumulative (both farms) mild production decrease of 70%; day 24, both farms quarantined; day 26, patient C returns to work, with lesions; day 27, lesion samples collected from patients B and C and 1 cow, farm 2; day 28, all cattle recovering.
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