Volume 18, Number 2—February 2012
Research
Characterization of Nipah Virus from Outbreaks in Bangladesh, 2008–2010
Michael K. Lo
, Luis Lowe, Kimberly B. Hummel, Hossain M.S. Sazzad, Emily S. Gurley, M. Jahangir Hossain, Stephen P. Luby, David M. Miller, James A. Comer, Pierre E. Rollin, William J. Bellini, and Paul A. Rota
, Luis Lowe, Kimberly B. Hummel, Hossain M.S. Sazzad, Emily S. Gurley, M. Jahangir Hossain, Stephen P. Luby, David M. Miller, James A. Comer, Pierre E. Rollin, William J. Bellini, and Paul A. RotaTable 3
Amino acid differences among available complete Nipah virus N gene open reading frame sequences*
| Sequence and accession no. | Amino acid position |
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G | 30 | 139 | 188 | 211 | 318 | 345 | 380 | 381 | 387 | 414 | 429 | 432 | 436 | 457 | 502 | 505 | 506 | 508 | 511 | 518 | 521 | |
| NiV/MY/HU/1999/CDC, AF212302 | M | T | S | E | Q | I | M | N | R | D | K | I | G | I | N | I | R | T | G | E | L | A |
| NiV/MY/PI/1999/1413, AJ564622 | M | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| NiV/MY/PI/1999/2794, AJ564621 | M | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| NiV/MY/PI/1999/0626, AJ627196 | M | . | R | . | . | . | I | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| NiV/MY/HU/1999/0128, AJ564623 | M | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| NiV/MY/HU/1999/UM1, AY029767 | M | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| NiV/MY/HU/1999/UM2, AY029768 | M | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| NiV/MY/BA/2000/TI, AF376747 | M | I | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| NiV/MY/BA/2010/MY, FN869553 | M | . | . | . | . | . | . | . | . | . | . | V | E | . | D | . | . | . | . | . | . | . |
| NiV/KH/BA/2004/KHM, AY858110 | M | . | . | . | . | . | . | . | . | . | . | V | E | . | D | T | . | . | . | G | P | T |
| NiV/BD/HU/2004/1, AY988601 | B | . | . | D | . | . | . | . | . | N | . | V | E | . | D | . | K | D | R | . | . | T |
| NiV/BD/HU/2004/FA, JN808858 | B | . | . | . | . | . | . | . | . | N | N | V | E | M | D | . | K | D | R | . | . | T |
| NiV/BD/HU/2004/RA2, JN808861 | B | . | . | . | . | . | . | . | . | N | . | V | E | . | D | . | K | D | R | . | . | T |
| NiV/BD/HU/2004/RAJ, JN808862 | B | . | . | . | . | . | . | I | . | N | . | V | E | M | D | . | K | D | R | . | . | T |
| NiV/BD/HU/2008/MA, JN808857 | B | . | . | . | . | . | . | . | . | N | . | V | E | . | D | . | K | D | R | . | . | T |
| NiV/BD/HU/2008/RA, JN808863 | B | . | . | . | . | . | . | . | . | N | . | V | E | . | D | . | K | D | R | . | . | T |
| NiV/BD/HU/2010/FA1, JN808864 | B | . | . | . | . | . | . | . | K | N | . | V | E | . | D | . | K | D | R | . | . | T |
| NiV/BD/HU/2010/GO, JN808860 | B | . | . | . | . | V | . | . | . | N | . | V | E | . | D | . | K | D | R | . | . | T |
| NiV/BD/HU/2010/FA2, JN808859 | B | . | . | . | . | . | . | . | . | N | . | V | E | . | D | . | K | D | R | . | . | T |
| NiV/IN/HU/2007/FG, FJ513078 | B | . | . | . | R | . | . | . | . | N | . | V | E | . | D | . | K | D | R | . | . | T |
*Dots indicate sequence identity with AF212302. NiV, Nipah virus; MY, Malaysia; HU, human; G, genotype classification; genotype M, sequences from Malaysia and Cambodia; genotype B, sequences from Bangladesh and India; T, threonine, S, serine; E, glutamate; Q, glutamine; I, isoleucine; M, methionine; N, asparagine; R, arginine; D, aspartate; K, lysine; G, glycine; V; valine; P, proline; PI, pig; BA, bat; KH, Cambodia; BD, Bangladesh; IN, India.
