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Volume 18, Number 2—February 2012

Research

Characterization of Nipah Virus from Outbreaks in Bangladesh, 2008–2010

Michael K. LoComments to Author , Luis Lowe, Kimberly B. Hummel, Hossain M.S. Sazzad, Emily S. Gurley, M. Jahangir Hossain, Stephen P. Luby, David M. Miller, James A. Comer, Pierre E. Rollin, William J. Bellini, and Paul A. Rota
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.K. Lo, L. Lowe, K.B. Hummel, D.M. Miller, J.A. Comer, P.E. Rollin, W.J. Bellini, P.A. Rota); International Centre for Diarrheal Disease Research, Bangladesh, Dhaka, Bangladesh (H.M.S. Sazzad, E.S. Gurley, M.J. Hossain, S.P. Luby)

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Table 3

Amino acid differences among available complete Nipah virus N gene open reading frame sequences*

Sequence and accession no. Amino acid position
G 30 139 188 211 318 345 380 381 387 414 429 432 436 457 502 505 506 508 511 518 521
NiV/MY/HU/1999/CDC, AF212302 M T S E Q I M N R D K I G I N I R T G E L A
NiV/MY/PI/1999/1413, AJ564622 M . . . . . . . . . . . . . . . . . . . . .
NiV/MY/PI/1999/2794, AJ564621 M . . . . . . . . . . . . . . . . . . . . .
NiV/MY/PI/1999/0626, AJ627196 M . R . . . I . . . . . . . . . . . . . . .
NiV/MY/HU/1999/0128, AJ564623 M . . . . . . . . . . . . . . . . . . . . .
NiV/MY/HU/1999/UM1, AY029767 M . . . . . . . . . . . . . . . . . . . . .
NiV/MY/HU/1999/UM2, AY029768 M . . . . . . . . . . . . . . . . . . . . .
NiV/MY/BA/2000/TI, AF376747 M I . . . . . . . . . . . . . . . . . . . .
NiV/MY/BA/2010/MY, FN869553 M . . . . . . . . . . V E . D . . . . . . .
NiV/KH/BA/2004/KHM, AY858110 M . . . . . . . . . . V E . D T . . . G P T
NiV/BD/HU/2004/1, AY988601 B . . D . . . . . N . V E . D . K D R . . T
NiV/BD/HU/2004/FA, JN808858 B . . . . . . . . N N V E M D . K D R . . T
NiV/BD/HU/2004/RA2, JN808861 B . . . . . . . . N . V E . D . K D R . . T
NiV/BD/HU/2004/RAJ, JN808862 B . . . . . . I . N . V E M D . K D R . . T
NiV/BD/HU/2008/MA, JN808857 B . . . . . . . . N . V E . D . K D R . . T
NiV/BD/HU/2008/RA, JN808863 B . . . . . . . . N . V E . D . K D R . . T
NiV/BD/HU/2010/FA1, JN808864 B . . . . . . . K N . V E . D . K D R . . T
NiV/BD/HU/2010/GO, JN808860 B . . . . V . . . N . V E . D . K D R . . T
NiV/BD/HU/2010/FA2, JN808859 B . . . . . . . . N . V E . D . K D R . . T
NiV/IN/HU/2007/FG, FJ513078 B . . . R . . . . N . V E . D . K D R . . T

*Dots indicate sequence identity with AF212302. NiV, Nipah virus; MY, Malaysia; HU, human; G, genotype classification; genotype M, sequences from Malaysia and Cambodia; genotype B, sequences from Bangladesh and India; T, threonine, S, serine; E, glutamate; Q, glutamine; I, isoleucine; M, methionine; N, asparagine; R, arginine; D, aspartate; K, lysine; G, glycine; V; valine; P, proline; PI, pig; BA, bat; KH, Cambodia; BD, Bangladesh; IN, India.

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