Recombination of Human Coxsackievirus B5 in Hand, Foot, and Mouth Disease Patients, China
Jian-Feng Han, Tao Jiang, Xing-Liang Fan, Li-Ming Yang, Man Yu, Rui-Yuan Cao, Jun-Zhi Wang, E-De Qin, and Cheng-Feng Qin
Author affiliations: State Key Laboratory of Pathogen and Biosecurity, Beijing, People’s Republic of China (J.-F. Han, T. Jiang, L.-M. Yang, M. Yu, R.-Y. Cao, E.-D. Qin, C.-F. Qin); Beijing Institute of Microbiology and Epidemiology, Beijing, People’s Republic of China (J.-F. Han, T. Jiang, L.-M. Yang, M. Yu, R.-Y. Cao, E.-D. Qin, C-.F. Qin); National Institutes for Food and Drug Control, Beijing (X.-L. Fan, J.-Z. Wang)
Figure. . Phylogenetic analysis of selected human coxsackievirus B (CBV) strains from different origins based on the viral protein 1 gene sequences. The neighbor-joining tree was generated by using MEGA4 software (www.megasoftware.net), and the prototype strain of coxsackievirus A (CAV) 16 was used as outgroup. The Changchun strains isolated in this study are indicated by triangles and other Chinese CBV5 strains are indicated by squares. Scale bar indicates nucleotide substitutions per site.
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