Volume 18, Number 3—March 2012
Research
Using Genotyping and Geospatial Scanning to Estimate Recent Mycobacterium tuberculosis Transmission, United States
Patrick K. Moonan
, Smita Ghosh, John E. Oeltmann, J. Steven Kammerer, Lauren S. Cowan, and Thomas R. Navin
, Smita Ghosh, John E. Oeltmann, J. Steven Kammerer, Lauren S. Cowan, and Thomas R. NavinTable 2
Demographic, behavioral, and clinical characteristics of persons involved in putative recent TB transmission events, by location, United States, 2005–2009*
| US Census region, no. (%) persons,† and main characteristics | Odds ratio (99% CI) | Wald p value |
|---|---|---|
| West, 11,550 (31.3) | ||
| Mycobacterium bovis TB | 4.4 (2.2–8.8) | <0.0001 |
| US-born | 2.4 (4.3–4.7) | <0.0001 |
| East-Asian phylogenetic lineage TB | 2.4 (1.4–4.2) | <0.0001 |
| Hispanic | 2.3 (1.7–3.0) | <0.0001 |
| Homeless‡ | 1.9 (1.5–2.9) | <0.0001 |
| Midwest, 10,502 (28.5) | ||
| US-born | 2.5 (2.1–3.1) | <0.0001 |
| Black, non-Hispanic | 2.1 (1.7–2.6) | <0.0001 |
| Substance abuser§ | 1.4 (1.3–1.6) | <0.0001 |
| Northeast, 6,090 (16.5) | ||
| Hispanic | 2.1 (1.5–3.0) | <0.0001 |
| East-Asian phylogenetic lineage TB | 2.0 (1.1–3.6) | 0.001 |
| US-born | 1.6 (1.2–2.1) | <0.0001 |
| Substance abuser§ | 1.6 (1.2–2.1) | <0.0001 |
| South 8,718 (23.7) | ||
| Black, non-Hispanic | 3.6 (1.5–8.6) | <0.0001 |
| US-born | 3.2 (2.5–4.2) | <0.0001 |
| Euro-American phylogenetic lineage TB | 2.2 (1.1, 4.3) | 0.004 |
| Substance abuser§ | 1.5 (1.1–4.3) | <0.0001 |
| Total, 36,860 |
*TB, tuberculosis.
†Column percentage.
‡Self-reported homelessness within 12 mo preceding TB diagnosis.
§Self-reported excess alcohol consumption, injection drug use, or noninjection drug use within 12 mo preceding TB diagnosis.
