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Volume 18, Number 5—May 2012

Dispatch

Rhabdomyolysis Associated with Antimicrobial Drug–Resistant Mycoplasma pneumoniae

Tomohiro OishiComments to Author , Mitsuo Narita, Hitomi Ohya, Takayuki Yamanaka, Yuta Aizawa, Mai Matsuo, Masamichi Matsunaga, Shinya Tsukano, and Testuo Taguchi
Author affiliations: Niigata University Medical and Dental Hospital, Niigata, Japan (T. Oishi); Sapporo Tokushukai Hospital, Sapporo, Japan (M. Narita); Kanagawa Prefectural Institute of Public Health, Kanagawa, Japan (H. Ohya); Niigata Prefectural Shibata Hospital, Niigata (T. Yamanaka, Y. Aizawa, M. Matsuo, M. Matsunaga, S. Tsukano, T. Taguchi)

Main Article

Table

Laboratory test results for a 7-year-old patient with rhabdomyolysis associated with antimicrobial drug–resistant Mycoplasma pneumoniae, Japan, June 22–July 23, 2010*

Laboratory test Laboratory value, by days after onset of fever
7 d 9 d 13 d 17 d 23 d 31 d
Leukocytes, ×109 cells/L 6.2 8.0 11.8 7.3 5.9 4.7
C-reactive protein, mg/L 27 7 4 1 <1 <1
Creatine phosphokinase, mg/L 12,159 12,918 10,937 5,839 1,855 130
Aspartate aminotransferase, IU/L 161 203 169 94 101 24
Alanine aminotransferase, IU/L 83 205 284 209 162 37
Lactate dehydrogenase, IU/L 691 553 451 358 294 234
Creatinine, μmol/L 31.8 23.0 30.1 32.7 30.9 29.2
Urine myoglobin, μg/L 39,900 NT 2,500 NT 10 <10
Urine erythrocytes 3+ 3+ ±
Serum interleukin-18, pg/mL 612 519 NT NT 367 232
Serum tumor necrosis factor–α, pg/mL 3.48 3.38 NT NT 2.03 1.64
M. pneumoniae titer 1,280 10,240 NT NT NT NT

*NT, not tested.

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