Figure. . . A 7-day old, female, Schmallenberg virus–positive calf showing severe central nervous system dysfunctions (A–C) and lesions (D–E). A) Spontaneously lying down; B–C) standing with assistance; D–G) porcencephaly, either with the encephalon in place (D–E) or extracted (F–G). The cerebral hemispheres were replaced by 2 thin-walled, fluid-filled cysts (diamonds) with some floating islets and peninsulae corresponding to preserved cortex (stars). The cerebrum was variably preserved, the occipital lobes were totally liquefied, and the outer layers of some parts of the temporal and frontal lobes were irregularly preserved. The cerebellum, brainstem, and diencephalon appeared normal in shape and volume.