Volume 18, Number 8—August 2012
CME ACTIVITY
Vaccination of Health Care Workers to Protect Patients at Increased Risk for Acute Respiratory Disease
Gayle P. Dolan
, Rebecca C. Harris, Mandy Clarkson, Rachel Sokal, Gemma Morgan, Mitsuru Mukaigawara, Hiroshi Horiuchi, Rachel Hale, Laura Stormont, Laura Béchard-Evans, Yi-Sheng Chao, Sergey Eremin, Sara Martins, John S. Tam, Javier Peñalver, Arina Zanuzdana, and Jonathan S. Nguyen-Van-Tam
, Rebecca C. Harris, Mandy Clarkson, Rachel Sokal, Gemma Morgan, Mitsuru Mukaigawara, Hiroshi Horiuchi, Rachel Hale, Laura Stormont, Laura Béchard-Evans, Yi-Sheng Chao, Sergey Eremin, Sara Martins, John S. Tam, Javier Peñalver, Arina Zanuzdana, and Jonathan S. Nguyen-Van-TamTable 4
Clinically defined outbreaks and clusters of ILI in a review of the vaccination of health care workers to protect patients at risk for acute respiratory disease*
| Study | Study design | Method of assessment | Measure of effect in patient population | Effect estimate (95% CI) |
|---|---|---|---|---|
| Oshitani et al. (28) | Prospective cohort | Defined as ILI >10% of total resident population. Mandatory reporting by survey. | OR, unadjusted facilities with >10 staff members vaccinated vs. those with <10 staff members vaccinated | 0.30 (0.09–0.69)† |
| Stevenson et al. (37) | Cross-sectional | No definition provided. Reporting by survey. | χ2 test for trend; logistic regression | χ2 p = 0.03; logistic regression p = 0.08 |
| Shugarman et al. (35) | Cross-sectional | Defined as >3 residents within a 72-h period with influenza-like symptoms, sudden onset of fever, or “feverishness” and >1 of the following respiratory symptoms; sore throat, runny nose, cough, or nasal congestion. Reporting by survey. | OR, facilities with staff vaccination coverage >55% and patient vaccination coverage >89%, vs. those with lower coverage | 0.39 (0.17–0.87)† |
*ILI, influenza-like illness; OR, odds ratio. Boldface indicates statistical significance.
†p value not reported.
