Seroprevalence and Cross-reactivity of Human Polyomavirus 9
Jérôme T.J. Nicol, Antoine Touzé, Rémy Robinot, Francoise Arnold, Elisa Mazzoni, Mauro Tognon, and Pierre Coursaget
Author affiliations: Institut National de la Santé et de la Recherche Médicale, Tours, France (J.T.J. Nicol, A. Touzé, R. Robinot, F. Arnold, P. Coursaget); Université François Rabelais, Tours (J.T.J. Nicol, A. Touzé, R. Robinot, F. Arnold, P. Coursaget); and School of Medicine, University of Ferrara, Ferrara, Italy (E. Mazzoni, M. Tognon)
Figure 1. . Cross-reactivity between human polyomavirus 9 (HPyV9), simian lymphotropic polyomavirus (LPyV), and Merkel cell polyomavirus (MCPyV) virus–like particles (VLPs). Correlation between A) seroreactivity of 325 serum samples from children and adults in Italy against HPyV9 VLPs and B) MCPyV VLPs and HPyV9 VLPs was analyzed by ELISA. Each point represents 1 serum sample. Correlation coefficients (Spearman ρ) were determined by using XLStat software (Addinsoft, Paris, France). Correlation coefficient was 0.842 in panel B and 0.139 in panel A. C) Titers of 15 serum samples from adults against HPyV9 VLPs and LPyV VLPs. Each point represents 1 serum sample. OD, optical density.
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