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Volume 18, Number 8—August 2012

Dispatch

Seroprevalence and Cross-reactivity of Human Polyomavirus 9

Jérôme T.J. Nicol, Antoine Touzé, Rémy Robinot, Francoise Arnold, Elisa Mazzoni, Mauro Tognon, and Pierre CoursagetComments to Author 
Author affiliations: Institut National de la Santé et de la Recherche Médicale, Tours, France (J.T.J. Nicol, A. Touzé, R. Robinot, F. Arnold, P. Coursaget); Université François Rabelais, Tours (J.T.J. Nicol, A. Touzé, R. Robinot, F. Arnold, P. Coursaget); and School of Medicine, University of Ferrara, Ferrara, Italy (E. Mazzoni, M. Tognon)

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Table

Cross-competition between HPyV9, LPyV, and MCPyV VP1 in serum samples reactive against HPyV9 and LPyV VP1 virus-like particles*

Serum sample no. HPyV9 reactivity (OD) after preincubation with
LPyV reactivity (OD) after preincubation with
Control HPyV9 LPyV MCPyV Control HPyV9 LPyV MCPyV
H1 0.988 0.054 0.737 0.943 0.848 0.049 0.036 0.841
H2 1.083 0.128 0.737 1.018 1.007 0.128 0.104 0.995
H3 1.154 0.100 0.921 1.128 1.080 0.073 0.061 1.159
H4 2.147 0.164 1.308 1.869 1.680 0.126 0.100 1.629
H5 2.256 0.195 2.023 2.152 2.525 0.349 0.153 2.671
H6 1.610 0.127 0.846 1.544 2.068 0.099 0.095 2.179
H7 1.223 0.088 0.577 1.456 1.816 0.069 0.062 1.828
H8 1.136 0.017 0.629 0.935 0.599 0.015 0.162 0.545
H9 0.732 0.055 0.437 0.648 0.441 0.119 0.075 0.448
H10 1.216 0.036 0.683 1.057 0.771 0.045 0.032 0.659
H11 1.489 0.070 1.114 1.303 0.801 0.203 0.070 0.522
H12 1.406 0.016 0.776 1.265 0.885 0.041 0.032 0.858
H13 1.682 0.042 0.944 1.199 0.853 0.168 0.065 0.547
H14 2.424 0.061 1.566 2.145 1.536 0.064 0.058 1.516
H15 2.843 0.067 2.109 2.611 2.339 0.075 0.318 2.205

*HPyV9, human polyomavirus 9; LPyV, simian lymphotropic polyomavirus; MCPyV, Merkel cell polyomavirus; VP1, viral protein 1; OD, optical density. Fifteen serum samples from blood donors reactive against HPyV9 and LPyV VP1 virus-like particles were preincubated with HPyV9, LPyV, or MCPyV VLPs.

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