Volume 19, Number 10—October 2013
Dispatch
Subclinical Avian Influenza A(H5N1) Virus Infection in Human, Vietnam
Mai Quynh Le
, Peter Horby, Annette Fox, Hien Tran Nguyen, Hang Khanh Le Nguyen, Phuong Mai Vu Hoang, Khanh Cong Nguyen, Menno D. de Jong, Rienk E. Jeeninga, H. Rogier van Doorn, Jeremy Farrar, and Heiman F.L. Wertheim
, Peter Horby, Annette Fox, Hien Tran Nguyen, Hang Khanh Le Nguyen, Phuong Mai Vu Hoang, Khanh Cong Nguyen, Menno D. de Jong, Rienk E. Jeeninga, H. Rogier van Doorn, Jeremy Farrar, and Heiman F.L. Wertheim
Table 2
Amino acid changes detected in first passage of full-genome sequence analysis of influenza A(H5N1) virus isolate from subclinical human infection, Vietnam
| Gene and mutation |
Mutation frequency, % |
| Polybasic 2, n = 112 | |
| S107N | 15 |
| I261T | 2 |
| K312R | 15 |
| Nucleoprotein, n = 125 | |
| I33V | 48 |
| H52Y | 50 |
| R77K | 45 |
| T395N | 49 |
| Polymerase, n = 51 | |
| A20T | 12 |
| D27S | 12 |
| V63A | 29 |
| T85T | 33 |
| K142R | 12 |
| Y241C | 45 |
| Q259P | 33 |
| L261M | 29 |
| A263T | 43 |
| D272E | 12 |
| V323I | 2 |
| E352D | 12 |
| R353K | 29 |
| R391K | 29 |
| S400P | 35 |
| A404S | 29 |
| D547N | 2 |
| A552T | 37 |
| N614T | 29 |
| G631S | 29 |
| S648C | 2 |
| L711I | 2 |
| Polybasic 1, n = 129 | |
| K54E | 22 |
| S158N | 49 |
| T182I | 2 |
| N314S | 2 |
| D383E | 30 |
| L384I | 7 |
| I525V | 9 |
| S633N | 2 |
| K635R | 19 |
| Hemagglutinin, n = 244 | |
| T9A | 49 |
| L82M | 36 |
| S139T | 6 |
| S152P | 36 |
| D199N | 2 |
| F455Y | 1 |
| K461R | 8 |
| Neuraminidase, n = 177 | |
| I8V | 16 |
| V13I | 27 |
| I16V | 21 |
| A46T | 14 |
| T64A | 1 |
| A66S | 1 |
| H106N | 1 |
| M107L | 23 |
| V143I | 10 |
| T168I | 2 |
| G200R | 49 |
| A212T | 1 |
| S265A | 36 |
| T312E | 1 |
| M318V | 26 |
| I326V | 21 |
| N346H | 13 |
| V369M | 19 |
| Nonstructural 1, n = 145 | |
| S73P | 11 |
| D87E | 6 |
| M118I | 28 |
| V123I | 28 |
| E148K | 1 |
| S166G | 25 |
| M217L | 1 |
| T220A | 6 |
Page created: September 16, 2013
Page updated: September 16, 2013
Page reviewed: September 16, 2013
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