Volume 19, Number 11—November 2013
Dispatch
Evidence of Vaccine-related Reassortment of Rotavirus, Brazil, 2008–2010
Tatiana Lundgren Rose
, Marcelle Figueira Marques da Silva1, Mariela Martinéz Goméz1, Hugo Reis Resque, Maria Yury Travassos Ichihara, Eduardo de Mello Volotão, and José Paulo Gagliardi Leite
, Marcelle Figueira Marques da Silva1, Mariela Martinéz Goméz1, Hugo Reis Resque, Maria Yury Travassos Ichihara, Eduardo de Mello Volotão, and José Paulo Gagliardi Leite
Table 2
Nucleotide similarity values when comparing the Brazilian G1P[8] samples with the Rotarix strain gene segments and genotype constellation of selected human group A rotaviruses*
| Protein encoded by genes† |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strain names‡ | Genotype constellation | VP7 | VP4 | VP6 | VP1 | VP2 | VP3 | NSP1 | NSP2 | NSP3 | NSP4 | NSP5 |
| SE15901–09 | Vaccine | G1 100% | P[8] 100% | I1 100% | R1 100% | C1 100% | M1 100% | A1 100% | N1 100% | T1 100% | E1 100% | H1 100% |
| MA19006–10 | Vaccine | G1 100% | P[8] 99% | I1 99% | R1 99% | C1 98% | M1 99% | A1 98% | N1 100% | T1 100% | E1 99% | H1 98% |
| BA19391–10 | Vaccine | G1 100% | P[8] 99% | I1 100% | R1 99% | C1 98% | M1 100% | A1 100% | N1 100% | T1 100% | E1 99,6% | H1 100% |
| ES15221–08 | Wa-like (ES) | G1 94% | P[8] 90% | I1 90% | R1 100% | C1 90% | M1 93% | A1 92% | N1 91% | T1 97% | E1 92% | H1 92% |
| SE16800–09 | Wa-like (SE) | G1 94% | P[8] 92% | I1 89% | R1 97% | C1 90% | M1 96% | A1 92% | N1 88% | T1 98% | E1 98% | H1 92% |
| PE17888–09 | Wa-like (PE) | G1 94% | P[8] 92% | I1 90% | R1 94% | C1 91% | M1 93% | A1 93% | N1 90% | T1 97% | E1 94% | H1 93% |
| MA19013–10 | Wa-like (MA) | G1 95% | P[8] 93% | I1 92% | R1 95% | C1 92% | M1 95% | A1 94% | N1 92% | T1 97% | E1 94% | H1 93% |
| MA19030–10 | Wa/AU-1 reassortant | G1 93% | P[8] 91% | X | R1 93% | X | M1 94% | A1 93% | N1 89% | T3 76% | E1 92% | H1 93% |
| Wa | Wa-like | G1 | P[8] | I1 | R1 | C1 | M1 | A1 | N1 | T1 | E1 | H1 |
| DS-1 | DS-1-like | G2 | P[4] | I2 | R2 | C2 | M2 | A2 | N2 | T2 | E2 | H2 |
| AK26 | Wa/DS-1 reassortant | G2 | P[4] | I2 | R2 | C2 | M2 | A2 | N1 | T2 | E2 | H2 |
| 6809 | Wa/DS-1 reassortant | G8 | P[6] | I2 | R1 | C1 | M1 | A1 | N1 | T1 | E1 | H1 |
| Matlab13 | Wa/DS-1 reassortant | G12 | P[6 | I1 | R1 | C1 | M1 | A1 | T2 | T1 | E1 | H1 |
| Mani-253 | Wa/DS-1 reassortant | G4 | P[4] | I1 | R1 | C1 | M2 | A8 | N1 | T1 | E1 | H1 |
| AU-1 | AU-1-like | G3 | P[9] | I3 | R3 | C3 | M3 | A3 | N3 | T3 | E3 | H3 |
| T152 | AU-1-like | G12 | P[9] | I3 | R3 | C3 | M3 | A12 | N3 | T3 | E3 | H6 |
| K8 | Wa/AU-1 reassortant | G1 | P[9] | I1 | R3 | C3 | M3 | A1 | N1 | T3 | E3 | H3 |
| Mani-265 | DS-1/AU-1 reassortant | G10 | P[6] | I2 | R2 | C2 | M2 | A3 | N2 | T7 | E2 | H2 |
*Wa-like, DS-1-like, AU-like genotypes are shown in green, red, and orange, respectively, and the P[6] genotype is shown in blue; X, indeterminate genotypes; –, no data.
†One sample for each group was chosen as representative and the average was shown.
‡Prefixes represent origins of circulating strains in Brazil: SE, Sergipe; BA, Bahia; MA, Maranhão; ES, Espirito Santo; PE, Pernambuco.
1These authors contributed equally to this article.
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