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Volume 19, Number 12—December 2013

Dispatch

Novel Variants of Clade 2.3.4 Highly Pathogenic Avian Influenza A(H5N1) Viruses, China

Min Gu, Guo Zhao, Kunkun Zhao, Lei Zhong, Junqing Huang, Hongquan Wan, Xiaoquan Wang, Wenbo Liu, Huimou Liu, Daxin Peng, and Xiufan LiuComments to Author 
Author affiliations: College of Veterinary Medicine, Yangzhou University, Yangzhou, China (M. Gu, G. Zhao, K. Zhao, L. Zhong, J. Huang, H. Wan, X. Wang, W. Liu, H. Liu, D. Peng, X. Liu); Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou (M. Gu, X. Wang, W. Liu, H. Liu, D. Peng, X. Liu)

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Table 1

Results of HI assays using Re-5 and k0602 antiserum for 7 avian influenza A(H5N1) viruses isolated in China, 2009–2012*

Isolate Isolation date Antibody titer, log2
Re-5 k0602
A/chicken/Jiangsu/WJ/2009(H5N1) 2009 Dec 4 8
A/chicken/Jiangsu/XZ/2010(H5N1) 2010 Mar 4 8
A/chicken/northern China/k0602/2010(H5N1) 2010 May 4 10
A/chicken/Shandong/k0603/2010(H5N1) 2010 Jun 4 10
A/chicken/eastern China/ZG56/2011(H5N1) 2011 Dec 4 5
A/chicken/eastern China/JX/2011(H5N1) 2011 Dec 3 7
A/chicken/eastern China/AH/2012(H5N1) 2012 Sep 4 1
Re-5 diagnostic antigen† NA 10 4

*Re-5 and k0602 antiserum were generated by vaccinating specific-pathogen free chickens with the commercial Re-5 vaccine (Qingdao Yebio Bioengineering Co., Ltd, Qingdao, China) and the oil-emulsified inactivated A/chicken/northern China/k0602/2010(H5N1) vaccine, respectively. HI titers against the homologous antigen/virus are shown in boldface. HI, hemagglutination inhibition; NA, not applicable.
†Qingdao Yebio Bioengineering Co., Ltd, China.

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