Skip directly to local search Skip directly to A to Z list Skip directly to navigation Skip directly to site content Skip directly to page options
CDC Home

Volume 19, Number 12—December 2013

Dispatch

Lack of MERS Coronavirus Neutralizing Antibodies in Humans, Eastern Province, Saudi Arabia

Stefanie Gierer1, Heike Hofmann-Winkler1, Waleed H. Albuali, Stephanie Bertram, Abdullah M. Al-Rubaish, Abdullah A. Yousef, Awatif N. Al-Nafaie, Amein K. Al-Ali, Obeid E. Obeid, Khaled R. Alkharsah, and Stefan Pöhlmann1Comments to Author 
Author affiliations: German Primate Center, Göttingen, Germany (S. Gierer, H. Hofmann-Winkler, S. Bertram, S. Pöhlmann); University of Dammam, Dammam, Saudi Arabia (W.H. Albuali, A.M. Al-Rubaish, A.A. Yousef, A.N. Al-Nafaie, A.K. Al-Ali, O.E. Obeid, K.R. Alkharsah).

Main Article

Figure 2

Analysis of serum samples with known neutralizing activity. Neutralization of transduction driven by the Middle East respiratory syndrome coronavirus spike protein (MERS-S) (A), G protein of vesicular stomatitis virus (B), and S protein of human coronavirus NL63 (NL63-S) (B) were determined as described for Figure 1, except that serum with known reactivity to MERS-S and NL63-S and serum from 2 patients at King Fahd Hospital of the University in Alkhobar, Saudi Arabia, that neutralized NL63-S–med

Figure 2. . Analysis of serum samples with known neutralizing activity. Neutralization of transduction driven by the Middle East respiratory syndrome coronavirus spike protein (MERS-S) (A), G protein of vesicular stomatitis virus (B), and S protein of human coronavirus NL63 (NL63-S) (C) were determined as described for Figure 1, except that serum with known reactivity to MERS-S and NL63-S and serum from 2 patients at King Fahd Hospital of the University in Alkhobar, Saudi Arabia, that neutralized NL63-S–mediated transduction (Figure 1, panel A) were analyzed. Transduction of target cells in the absence of serum was set at 100%.

Main Article

1These authors contributed equally to this article.

Top of Page

 

Past Issues

Select a Past Issue:

Art in Science - Selections from Emerging Infectious Diseases
Now available for order



CDC 24/7 – Saving Lives, Protecting People, Saving Money. Learn More About How CDC Works For You…

USA.gov: The U.S. Government's Official Web PortalDepartment of Health and Human Services
Centers for Disease Control and Prevention   1600 Clifton Rd. Atlanta, GA 30333, USA
800-CDC-INFO (800-232-4636) TTY: (888) 232-6348 - Contact CDC–INFO