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Volume 19, Number 2—February 2013

Synopsis

Lessons and Challenges for Measles Control from Unexpected Large Outbreak, Malawi

Andrea MinettiComments to Author , Matthew Kagoli, Agnes Katsulukuta, Helena Huerga, Amber Featherstone, Hazel Chiotcha, Delphine Noel, Cameron Bopp, Laurent Sury, Renzo Fricke, Marta Iscla, Northan Hurtado, Tanya Ducomble, Sarala Nicholas, Storn Kabuluzi, Rebecca F. Grais, and Francisco J. Luquero
Author affiliations: Author affiliations: Epicentre, Paris, France (A. Minetti, H. Huerga, D. Noel, S. Nicholas, R.F Grais, F.J. Luquero); Ministry of Health, Lilongwe, Malawi (M. Kagoli, A. Katsulukuta, S. Kabuluzi); Médecins Sans Frontières, Lilongwe (A. Featherstone, H. Chiotcha, C. Bopp); Médecins Sans Frontières, Paris, France (L. Sury, N. Hurtado); Médecins Sans Frontières, Brussels, Belgium (R. Fricke, T. Ducomble); Médecins Sans Frontières, Barcelona, Spain (M. Iscla)

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Table 3

Results from the vaccine effectiveness study in 8 districts, Malawi, 2010*

Vaccination status Total No. cases Attack rate, %† Vaccine effectiveness
Crude, % (95% CI) Adjusted, % (95% CI)‡
Unvaccinated
793
91
13.3
Referent
Referent
Vaccinated with MCV
1 dose§ 2512 62 2.4 82.0 (72.9–88.1) 83.9 (70.8–90.8)
2 doses¶ 1777 22 1.1 91.6 (84.7–95.4) 90.5 (79.7–95.5)

*Districts are Blantyre, Mzimba, Lilongwe, Thyolo, Chiradzulu, Mangochi, Balaka, and Machinga. MCV, measles-containing vaccine.
†Weighted and adjusted by the study design.
‡Adjusted by age, sex, and literacy of the caregiver.
§Routine immunization.
¶Routine immunization and 2008 supplementary immunization activities.

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