Occult Hepatitis B Virus Infection in Chacma Baboons, South Africa
Caroline Dickens, Michael C. Kew, Robert H. Purcell, and Anna Kramvis
Author affiliations: University of the Witwatersrand, Johannesburg, South Africa (C. Dickens, M.C. Kew, A. Kramvis); Groote Schuur Hospital, Cape Town, South Africa (M.C. Kew); National Institutes of Health, Bethesda, Maryland, USA (R.H. Purcell)
Figure 2. . . Liver tissue from Chacma baboon 9732, South Africa, showing lobular hepatitis. Liver tissue was obtained at necropsy, fixed in formalin, embedded in paraffin, and sectioned. A) Hematoxylin and eosin staining, showing a focus of mild lobular hepatitis but no evidence of interface hepatitis or bridging necrosis. Portal tracts are normal. B) Immunoperoxidase staining with polyclonal antibody against hepatitis B core antigen. Core antigen was detected in the occasional hepatocyte nucleus. Arrows indicate selected positive nuclei. Original magnifications ×400.
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