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Volume 19, Number 4—April 2013

Research

Detection of Spliced mRNA from Human Bocavirus 1 in Clinical Samples from Children with Respiratory Tract Infections

Andreas ChristensenComments to Author , Henrik Døllner, Lars Høsøien Skanke, Sidsel Krokstad, Nina Moe, and Svein Arne Nordbø
Author affiliations: Trondheim University Hospital, Trondheim, Norway (A. Christensen, H. Døllner, L.H. Skanke, S. Krokstad, N. Moe, S.A. Nordbø); Norwegian University of Science and Technology, Trondheim (A. Christensen, H. Døllner, N. Moe, S.A. Nordbø)

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Table 2

HBoV1 mRNA PCR results in NPAs in relation to HBoV1 DNAemia, a high HBoV1 DNA load, and monodection of HBoV1 DNA, Norway, 2007–2010*

Factor Total no. No. (%) HBoV1 mRNA+ No. (%) HBoV1 mRNA p value
HBoV1 DNAemia, n = 63 17 13 (77) 4 (23) p<0.001
No HBoV1 DNAemia
46
5 (11)
41 (89)
HBoV1 DNA load, n = 161
>106 copies/mL 59 33 (56) 26 (44) p<0.001
<106 copies/mL 102 0 102 (100)
>108 copies/mL 18 17 (94) 1 (6) p<0.001
<108 copies/mL
143
16 (11)
127 (89)
Monodection of HBoV1 DNA, n = 161 43 14 (33) 29 (67) p = 0.022
Multiple virus detections 118 19 (16) 99 (84)

*HBoV1, human bocavirus 1; NPAs, nasopharyngeal aspirates; HBoV1 DNAemia, HBoV1 viremia.

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