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Volume 19, Number 6—June 2013
Dispatch

BSE-associated Prion-Amyloid Cardiomyopathy in Primates

Susanne Krasemann, Giulia Mearini, Elisabeth Krämer, Katja Wagenführ, Walter Schulz-Schaeffer, Melanie Neumann, Walter Bodemer, Franz-Josef Kaup, Michael Beekes, Lucie Carrier, Adriano Aguzzi1, and Markus Glatzel1Comments to Author 
Author affiliations: University Medical Center Hamburg-Eppendorf, Hamburg, Germany (S. Krasemann, G. Mearini, E. Krämer, M. Neumann, L. Carrier, M. Glatzel); Robert Koch Institute, Berlin, Germany (K. Wagenführ, M. Beekes); University Hospital Göttingen, Göttingen, Germany (W. Schulz-Schaeffer); German Primate Center, Göttingen (W. Bodemer, F.-J. Kaup); University of Zurich, Zurich, Switzerland (A. Aguzzi)

Main Article

Table

Characteristics of 3 rhesus macaques in study of BSE-associated prion-amyloid cardiomyopathy*

Primate Age at inoculation Time to clinical disease, mo Disease duration, wk Cardiac PrPSc Signs of cardiac distress at autopsy
BSE inoculated 8 y 49 4 Neg Neg
5 y 59 18 Pos Pos
1 y 61 4 Neg Neg
Control 8 mo NA NA Neg Neg
17 y NA NA Neg Neg
19 y NA NA Neg Neg

*BSE, bovine spongiform encephalopathy; Neg, negative; Pos, positive; NA, not applicable.

Main Article

1These authors contributed equally to this article.

Page created: May 20, 2013
Page updated: May 20, 2013
Page reviewed: May 20, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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