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Volume 19, Number 7—July 2013

Research

Influence of Pneumococcal Vaccines and Respiratory Syncytial Virus on Alveolar Pneumonia, Israel

Daniel M. WeinbergerComments to Author , Noga Givon-Lavi, Yonat Shemer-Avni, Jacob Bar-Ziv, Wladimir J. Alonso, David Greenberg, and Ron Dagan
Author affiliations: Yale School of Public Health, New Haven, Connecticut, USA (D.M. Weinberger); National Institutes of Health, Bethesda, Maryland, USA (D.M. Weinberger, W.J. Alonso); Soroka University Medical Center, Beer-Sheva, Israel (N. Givon-Lavi, Y. Shemer-Avni, D. Greenberg); Ben-Gurion University of the Negev, Beer-Sheva (N. Givon-Lavi, Y. Shemer-Avni, D. Greenberg, R. Dagan); Hadassah University Medical Center, Jerusalem, Israel (J. Bar-Ziv)

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Table 2

Impact of pneumococcal conjugate vaccine from different models, southern Israel*

Age group, mo. Fit to 2004–05 through 2011–12
Fit to 2004–05 through 2010–11 (excluding 2011–12)
Full model Model without RSV† Unadjusted‡ Full model Model without RSV† Unadjusted‡
<6 −31.5 (−50.6 to −14.5) −30.7 (−57.2 to 9.7) −20.0 (−70.2 to 76.5) −27.9 (−62.9 to 9.2) −5.2 (−68.5 to 83.9) +22.3 (−81.5 to +106.0)
6–17 −40.5 (−52.1 to −31.5) −39.6 (−52.7 to −26.0) −36.0 (−63.4 to 4.6) −36.3 (−53.6 to −19.7) −29.9 (−53.7 to –7.8) −20.0 (−69.5 to +44.0)
17–35 −33.6 (−41.5 to −25) −33.0 (−40.9 tp −23.1) −31.3 (−47.8 to −8.4) −33.3 (−45.0 to −16.0) −29.1 (−44.2 to –10.8) −25.4 (−55.0 to +11.1)

*Vaccine impact is the estimated percentage change in disease incidence associated with pneumococcal conjugate vaccine use. RSV, respiratory syncytial virus.
†Model fit with all predictors described in the methods section except for RSV activity.
‡Model fit with predictors for vaccine uptake and ethnicity only.

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