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Volume 19, Number 8—August 2013
Dispatch

Macrolide Resistance of Mycoplasma pneumoniae, South Korea, 2000–2011

Ki Bae Hong, Eun Hwa ChoiComments to Author , Hoan Jong Lee, Seong Yeon Lee, Eun Young Cho, Jae Hong Choi, Hyun Mi Kang, Jina Lee, Young Min Ahn, Yeon-Ho Kang, and Joon-Ho Lee
Author affiliations: Seoul National University Hospital, Seoul, South Korea (K.B. Hong, E.H. Choi, H.J. Lee, S.Y. Lee, E.Y. Cho, J.H. Choi, H.M. Kang); Seoul National University College of Medicine, Seoul (E.H. Choi, H.J. Lee); Seoul National University Bundang Hospital, Seongnam, South Korea (J. Lee); Seoul Eulji Hospital, Seoul (Y.M. Ahn); Korea Centers for Disease Control and Prevention, Seoul (Y.-H. Kang); Kangwon National University Hospital, Chuncheon, South Korea (J.-H. Lee)

Main Article

Table 2

MICs of tetracyclines and fluoroquinolones for Mycoplasma pneumoniae strains in a study of macrolide resistance, South Korea, 2000–2011*

Antimicrobial drug Strains with 23S rRNA mutation, n = 69
Strains without 23S rRNA mutation, n = 54
Range MIC50 MIC90 Range MIC50 MIC90
Tetracyclines
Tetracycline 0.016 to 0.5 0.06 0.25 0.016 to 0.5 0.06 0.25
Doxycycline
0.002 to 0.125
0.06
0.06

0.004 to 0.125
0.03
0.06
Fluoroquinolones
Levofloxacin 0.016 to 0.5 0.25 0.25 0.016 to 0.5 0.25 0.5
Ciprofloxacin 0.125 to 1.0 0.5 1.0 0.06 to 1.0 0.5 1.0
Moxifloxacin 0.008 to 0.06 0.016 0.06 0.004 to 0.06 0.016 0.06

*MIC50 and MIC90 are minimum inhibitory concentrations at which 50% and 90% of the isolates, respectively, were inhibited by the drug.

Main Article

Page created: July 19, 2013
Page updated: July 19, 2013
Page reviewed: July 19, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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