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Volume 19, Number 8—August 2013
Dispatch

Genotype GI.6 Norovirus, United States, 2010–2012

Eyal LeshemComments to Author , Leslie Barclay, Mary Wikswo, Everardo Vega, Nicole Gregoricus, Umesh D. Parashar, Jan Vinjé, and Aron J. Hall
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Figure 1

Phylogenetic typing results for GI.6 noroviruses, United States, 2010–2012. Representative outbreak nucleotide sequences were genotyped by region D (5). Sequences were downloaded, trimmed, and analyzed as described (5). In brief, a 3-parameter model, TPM1, with equal frequencies and invariable sites was run in PhyML 3.0 (www.atgc-montpellier.fr/phyml/binaries.php) as determined by jModel test by using the corrected Akaike information criterion. The best of 5 random trees was used to start the an

Figure 1. . Phylogenetic typing results for GI.6 noroviruses, United States, 2010–2012. Representative outbreak nucleotide sequences were genotyped by region D (5). Sequences were downloaded, trimmed, and analyzed as described (5). In brief, a 3-parameter model, TPM1, with equal frequencies and invariable sites was run in PhyML 3.0 (www.atgc-montpellier.fr/phyml/binaries.php) as determined by jModel test by using the corrected Akaike information criterion. The best of 5 random trees was used to start the analysis, and the approximate likelihood ratio test was used for branch support. GI.6 reference sequences (GenBank accession nos. GQ856463| GI.6 Beijing and AJ277615| GI.6 Sindlesham) were included. Two clusters of genetically related outbreaks (cluster A and cluster B) are marked by brackets. *The distance of GI.1 Norwalk to the nearest GI.6 cluster is 2.29 substitutions per site. Scale bar indicates nucleotide substitutions per site for the phylogenetic tree.

Main Article

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Page created: July 19, 2013
Page updated: July 19, 2013
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The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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