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Volume 20, Number 1—January 2014
Letter

Indigenous Hepatitis E Virus Genotype 1 Infection, Uruguay

Santiago Mirazo, Victoria Mainardi, Natalia Ramos, Solange Gerona, Andrea Rocca, and Juan ArbizaComments to Author 
Author affiliations: Facultad de Ciencias, Universidad de la República, Montevideo, Uruguay (S. Mirazo, N. Ramos, J. Arbiza); Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay (V. Mainardi, S. Gerona, A. Rocca)

Main Article

Figure

Phylogenetic tree of the Hepatitis E virus constructed on the basis of A) the partial 137-nt open reading frame (ORF) 2–3 overlapping region and B) the 244-nt sequence of the RNA dependent RNA polymerase within ORF1. Trees were generated by using the neighbor-joining method with the Kimura 2-parameter as the substitution model. The robustness of the trees was determined by bootstrap for 1,000 replicates. Values ≥70% are shown. Strains isolated in Uruguay are shown in boldface. The isolate of gen

Figure. Phylogenetic tree of the Hepatitis E virus constructed on the basis of A) the partial 137-nt open reading frame (ORF) 2–3 overlapping region and B) the 244-nt sequence of the RNA dependent RNA polymerase within ORF1. Trees were generated by using the neighbor-joining method with the Kimura 2-parameter as the substitution model. The robustness of the trees was determined by bootstrap for 1,000 replicates. Values ≥70% are shown. Strains isolated in Uruguay are shown in boldface. The isolate of genotype 1 detected in this study (He_Uy 16) clustered (98% bootstrap value) with genotype 1 strains from India and Latin America (Cub 11 and 13 and VNZ792). Scale bars indicate nucleotide substitutions per site.

Main Article

Page created: December 18, 2013
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