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Volume 21, Number 1—January 2015
Dispatch

WU Polyomavirus in Respiratory Epithelial Cells from Lung Transplant Patient with Job Syndrome

Erica A. Siebrasse, Diana V. Pastrana, Nang L. Nguyen, Annie Wang, Mark J. Roth, Steven M. Holland, Alexandra F. Freeman, John McDyer, Christopher B. Buck, and David WangComments to Author 
Author affiliations: Washington University School of Medicine, St. Louis, Missouri, USA (E.A. Siebrasse, N.L. Nguyen, A. Wang, D. Wang); National Institutes of Health, Bethesda, Maryland, USA (D.V. Pastrana, M.J. Roth, S.M. Holland, A.F. Freeman, C.B. Buck); University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA (J. McDyer)

Main Article

Figure 1

WU polyomavirus antigen in bronchoalveolar lavage specimens from lungs transplanted into a recipient (28-year-old woman) with Job syndrome. Immunohistochemical analysis of 293T cells transfected with pDEST26-WU–virus protein 1 and stained as follows. A) WU virus protein 1 monoclonal antibody (NN-Ab06). B) Isotype control. C) Mock transfected 293T cells stained with NN-Ab06. D) Bronchoalveolar lavage specimen stained with NN-Ab06 showing prominent dark staining of cells with enlarged nuclei and a

Figure 1. WU polyomavirus antigen in bronchoalveolar lavage specimens from lungs transplanted into a recipient (28-year-old woman) with Job syndrome. Immunohistochemical analysis of 293T cells transfected with pDEST26-WU–virus protein 1 and stained as follows. A) WU virus protein 1 monoclonal antibody (NN-Ab06). B) Isotype control. C) Mock transfected 293T cells stained with NN-Ab06. D) Bronchoalveolar lavage specimen stained with NN-Ab06 showing prominent dark staining of cells with enlarged nuclei and a ground glass appearance characteristic of viral cytopathic changes (arrows). E) Isotype control. Original magnifications ×400 in panels A–C and ×600 in panels D and E.

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Page created: December 19, 2014
Page updated: December 19, 2014
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