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Volume 21, Number 10—October 2015
Research

Evolutionary and Ecological Characterization of Mayaro Virus Strains Isolated during an Outbreak, Venezuela, 2010

Albert J. Auguste, Jonathan Liria, Naomi L. Forrester, Dileyvic Giambalvo, Maria Moncada, Kanya C. Long1, Dulce Morón, Nuris de Manzione, Robert B. Tesh, Eric S. Halsey, Tadeusz J. Kochel, Rosa Hernandez, Juan-Carlos Navarro, and Nikos VasilakisComments to Author 
Author affiliations: Author affiliations: University of Texas Medical Branch, Galveston, Texas, USA (A.J. Auguste, N.L. Forrester, K.C. Long, R.B. Tesh, S.C. Weaver); Universidad de Carabobo, Naguanagua-Valencia, Venezuela (J. Liria); Ciudad Universitaria, Caracas, Venezuela (D. Giambalvo, M. Moncada, D. Morón, R. Hernandez); Centro de Investigaciones de Virosis Hemorrágicas y Enfermedades Transmisibles, Guanare, Portuguesa State, Venezuela (N. de Manzione); US Naval Medical Research Unit No. 6, Lima, Peru (E.S. Halsey, T.J. Kochel); Universidad Central de Venezuela, Caracas (J.-C. Navarro)

Main Article

Table 4

Estimated dates of divergence derived from partial E2 and complete genome sequences for major Mayaro virus lineages, Venezuela, 2010*

Lineage Date for time of MRCA for partial E2–E1 sequences (95% HPD) Date for time of MRCA for complete genome sequences (95% HPD)
Venezuelan outbreak strains 2007 (2003–2009) 2008 (2007–2009)
Northeast Peruvian and Bolivian clade 1952 (1935–1967) 1966 (1940–1970)
South/Central Peruvian clade 1968 (1953–1980) 1977 (1967–1987)
Brazilian genotype D clade 1864 (1822–1904) 1872 (1836–1906)
Brazilian genotype L clade 1877 (1836–1915) 1905 (1882–1926)
Peruvian genotype N clade 1750 (1657–1833) 1746 (1658–1823)

*E, envelope; MRCA, most recent common ancestor; HPD, highest posterior density.

Main Article

1Current affiliation: Andrews University, Berrien Springs, Michigan, USA.

Page created: September 22, 2015
Page updated: September 22, 2015
Page reviewed: September 22, 2015
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