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Volume 21, Number 11—November 2015
Dispatch

RmtC and RmtF 16S rRNA Methyltransferase in NDM-1–Producing Pseudomonas aeruginosa

Mohibur Rahman, Kashi Nath PrasadComments to Author , Ashutosh Pathak, Binod Kumar Pati, Avinash Singh, Cristina M. Ovejero, Saheem Ahmad, and Bruno Gonzalez-Zorn
Author affiliations: Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India (M. Rahman, K.N. Prasad, A. Pathak, B.K. Pati, A. Singh); Integral University, Lucknow (M. Rahman, S. Ahmad); Complutense University of Madrid, Madrid, Spain (C.M. Overjero, B. Gonzalez-Zorn)

Main Article

Table

MICs of different antimicrobial drugs, resistance genes, and association of ISEcp1 with rmtC in 3 Pseudomonas aeruginosa clinical isolates, India, 2013–2014*

Isolate MIC, mg/L
 Antimicrobial drug resistance genes Association of ISEcp1 with rmtC
CAZ CTX FEP ATM CPS TZP IPM MER COL AK G
KnPa1A >512 >512 512 8 256 64 16 32 2 >512 >512 blaNDM-1, rmtC Intact
KnPa1B 256 >512 >512 16 128 32 16 64 2 >512 >512 blaNDM-1, rmtC,rmtF, blaCMY-2 Truncated
KnPa1C >512 >512 512 16 128 64 32 128 2 >512 >512 blaNDM-1, rmtC, blaTEM-1, blaCTX-M-15 Truncated

*CAZ, ceftazidime; CTX, cefotaxime; FEP, cefepime; ATM, aztreonam; CPS, cefoperazone/sulbactam; TZP, piperacillin/tazobactam; IPM, imipenem; MER, meropenem; COL, colistin; AK, amikacin; G, gentamicin.

Main Article

Page created: October 19, 2015
Page updated: October 19, 2015
Page reviewed: October 19, 2015
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